Association Between Obesity and Depressive Disorder in Adolescents at High Risk for Depression

Overview

Journal Int J Obes (Lond)

Specialty Endocrinology

Date 2013 Jul 27

PMID 23887062

Citations 7

Authors

G Hammerton

A Thapar

A K Thapar

Affiliations

Soon will be listed here.

Abstract

Objective: To examine the relationship between Body Mass Index (BMI) and depressive disorder in adolescents at high risk for depression.

Design: Prospective longitudinal 3-wave study of offspring of parents with recurrent depression. Replication in population-based cohort study.

Subjects: Three hundred and thirty-seven families where offspring were aged 9-17 years at baseline and 10-19 years at the final data point. Replication sample of adolescents from population-based cohort study aged 11-13 years at first assessment and 14-17 years at follow-up.

Measurements: High risk sample used BMI, skin-fold thickness, Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV)-defined major depressive disorder and depression symptoms using the Child and Adolescent Psychiatric Assessment (CAPA). Replication sample used BMI, DSM-IV depressive disorder and depression symptoms using the Development and Well-Being Assessment (DAWBA).

Results: Two hundred and eighty-nine adolescents were included in the primary analyses. The mean BMI for each age group in this sample were significantly higher than population norms. There was no significant longitudinal association between categories of weight (or BMI) and new onset depressive disorder or depression symptoms. Similar results were found for skin-fold thickness. The association was also tested in a replication population-based sample and found to be non-significant in the subsample of offspring with mothers who had experienced recurrent depression in the past. BMI at age 12 years was, however, a significant predictor of depression symptoms but not of depressive disorder at age 15 years for the total unselected population.

Conclusion: BMI does not significantly predict the development of depression in the offspring of parents with recurrent depression.

Citing Articles

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References

Goodman R, Ford T, Richards H, Gatward R, Meltzer H . The Development and Well-Being Assessment: description and initial validation of an integrated assessment of child and adolescent psychopathology. J Child Psychol Psychiatry. 2000; 41(5):645-55. View

Wardle J, Williamson S, Johnson F, Edwards C . Depression in adolescent obesity: cultural moderators of the association between obesity and depressive symptoms. Int J Obes (Lond). 2006; 30(4):634-43. DOI: 10.1038/sj.ijo.0803142. View

Mustillo S, Worthman C, Erkanli A, Keeler G, Angold A, Costello E . Obesity and psychiatric disorder: developmental trajectories. Pediatrics. 2003; 111(4 Pt 1):851-9. DOI: 10.1542/peds.111.4.851. View

Cole T, Bellizzi M, Flegal K, Dietz W . Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000; 320(7244):1240-3. PMC: 27365. DOI: 10.1136/bmj.320.7244.1240. View

Angold A, Costello E . A test-retest reliability study of child-reported psychiatric symptoms and diagnoses using the Child and Adolescent Psychiatric Assessment (CAPA-C). Psychol Med. 1995; 25(4):755-62. DOI: 10.1017/s0033291700034991. View

Boyd A, Golding J, Macleod J, Lawlor D, Fraser A, Henderson J . Cohort Profile: the 'children of the 90s'--the index offspring of the Avon Longitudinal Study of Parents and Children. Int J Epidemiol. 2012; 42(1):111-27. PMC: 3600618. DOI: 10.1093/ije/dys064. View

Cole T, Freeman J, Preece M . British 1990 growth reference centiles for weight, height, body mass index and head circumference fitted by maximum penalized likelihood. Stat Med. 1998; 17(4):407-29. View

Goodman A, Heiervang E, Collishaw S, Goodman R . The 'DAWBA bands' as an ordered-categorical measure of child mental health: description and validation in British and Norwegian samples. Soc Psychiatry Psychiatr Epidemiol. 2010; 46(6):521-32. DOI: 10.1007/s00127-010-0219-x. View

Skilton M, Moulin P, Terra J, Bonnet F . Associations between anxiety, depression, and the metabolic syndrome. Biol Psychiatry. 2007; 62(11):1251-7. DOI: 10.1016/j.biopsych.2007.01.012. View

10.

Petersen A, Crockett L, Richards M, Boxer A . A self-report measure of pubertal status: Reliability, validity, and initial norms. J Youth Adolesc. 2013; 17(2):117-33. DOI: 10.1007/BF01537962. View

11.

Reeves G, Postolache T, Snitker S . Childhood Obesity and Depression: Connection between these Growing Problems in Growing Children. Int J Child Health Hum Dev. 2008; 1(2):103-114. PMC: 2568994. View

12.

Angold A, Costello E . The Child and Adolescent Psychiatric Assessment (CAPA). J Am Acad Child Adolesc Psychiatry. 2000; 39(1):39-48. DOI: 10.1097/00004583-200001000-00015. View

13.

de Wit L, van Straten A, van Herten M, Penninx B, Cuijpers P . Depression and body mass index, a u-shaped association. BMC Public Health. 2009; 9:14. PMC: 2631467. DOI: 10.1186/1471-2458-9-14. View

14.

Evans D, Charney D, Lewis L, Golden R, Gorman J, Krishnan K . Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry. 2005; 58(3):175-89. DOI: 10.1016/j.biopsych.2005.05.001. View

15.

Cortese S, Falissard B, Angriman M, Pigaiani Y, Banzato C, Bogoni G . The relationship between body size and depression symptoms in adolescents. J Pediatr. 2008; 154(1):86-90. DOI: 10.1016/j.jpeds.2008.07.040. View

16.

Pine D, Goldstein R, Wolk S, Weissman M . The association between childhood depression and adulthood body mass index. Pediatrics. 2001; 107(5):1049-56. DOI: 10.1542/peds.107.5.1049. View

17.

Goodman E, Whitaker R . A prospective study of the role of depression in the development and persistence of adolescent obesity. Pediatrics. 2002; 110(3):497-504. DOI: 10.1542/peds.110.3.497. View

18.

Anderson S, Cohen P, Naumova E, Jacques P, Must A . Adolescent obesity and risk for subsequent major depressive disorder and anxiety disorder: prospective evidence. Psychosom Med. 2007; 69(8):740-7. DOI: 10.1097/PSY.0b013e31815580b4. View

19.

Stunkard A, Faith M, Allison K . Depression and obesity. Biol Psychiatry. 2003; 54(3):330-7. DOI: 10.1016/s0006-3223(03)00608-5. View

20.

Revah-Levy A, Speranza M, Barry C, Hassler C, Gasquet I, Moro M . Association between Body Mass Index and depression: the "fat and jolly" hypothesis for adolescents girls. BMC Public Health. 2011; 11:649. PMC: 3223732. DOI: 10.1186/1471-2458-11-649. View