Ultrasound Elastography in the Head and Neck. Part II. Accuracy for Malignancy

Overview

Journal Cancer Imaging

Publisher Springer Nature

Specialties Oncology
Radiology

Date 2013 Jul 24

PMID 23876383

Citations 19

Authors

Kunwar S S Bhatia

Yolanda Y P Lee

Edmund H Y Yuen

Anil T Ahuja

Affiliations

Soon will be listed here.

Abstract

Ultrasound elastography (USE) describes a variety of ultrasound-based imaging techniques that measure tissue stiffness properties, and is currently under intense investigation for tissue characterization in several anatomic sites. This article summarizes the evidence regarding the accuracy of USE for malignancy in the head and neck. Currently, most published data pertains to small pilot studies with varied methodologies. Encouragingly, most studies have documented promising results for USE in terms of high accuracy for malignancy in thyroid nodules and cervical lymph nodes, which have surpassed conventional sonographic criteria. However, a minority of studies have documented opposite findings. USE seems to be suboptimal for salivary malignancies, and some evidence suggests that USE does not provide useful diagnostic information compared with conventional ultrasonography for miscellaneous neck masses. Further larger studies are required to validate these findings although, in view of the predominance of highly optimistic results for thyroid nodules and cervical lymph nodes, USE may become a useful ancillary technique in the routine diagnostic work-up of lesions in these tissues in the near future.

Citing Articles

Shear-wave elastographic imaging in choroidal melanomas: clinical and hemodynamic correlations.

Douglas K, Drakonaki E, Douglas V, Detorakis E Jpn J Ophthalmol. 2024; 68(5):523-530.

PMID: 39088115 DOI: 10.1007/s10384-024-01086-y.

Qualitative and Quantitative Diagnosis in Head and Neck Cancer.

Lopez F, Makitie A, de Bree R, Franchi A, de Graaf P, Hernandez-Prera J Diagnostics (Basel). 2021; 11(9).

PMID: 34573868 PMC: 8466857. DOI: 10.3390/diagnostics11091526.

Ultrasound Elastography for the Evaluation of Lymph Nodes.

Wang B, Guo Q, Wang J, Yu Y, Yi A, Cui X Front Oncol. 2021; 11:714660.

PMID: 34485150 PMC: 8415874. DOI: 10.3389/fonc.2021.714660.

Ultrasonographic Algorithm for the Assessment of Sentinel Lymph Nodes That Drain the Mammary Carcinomas in Female Dogs.

Stan F, Gudea A, Damian A, Gal A, Papuc I, Pop A Animals (Basel). 2020; 10(12).

PMID: 33321917 PMC: 7763578. DOI: 10.3390/ani10122366.

Optimized algorithm in solid thyroid nodule elastography.

Wu H, Chen Q, Liu Y, Chen J, Deng W Oncol Lett. 2020; 20(5):248.

PMID: 32994811 PMC: 7509691. DOI: 10.3892/ol.2020.12111.

References

Shuzhen C . Comparison analysis between conventional ultrasonography and ultrasound elastography of thyroid nodules. Eur J Radiol. 2011; 81(8):1806-11. DOI: 10.1016/j.ejrad.2011.02.070. View

Gu J, Du L, Bai M, Chen H, Jia X, Zhao J . Preliminary study on the diagnostic value of acoustic radiation force impulse technology for differentiating between benign and malignant thyroid nodules. J Ultrasound Med. 2012; 31(5):763-71. DOI: 10.7863/jum.2012.31.5.763. View

Lippolis P, Tognini S, Materazzi G, Polini A, Mancini R, Ambrosini C . Is elastography actually useful in the presurgical selection of thyroid nodules with indeterminate cytology?. J Clin Endocrinol Metab. 2011; 96(11):E1826-30. DOI: 10.1210/jc.2011-1021. View

Zhang Y, Xu H, He Y, Liu C, Guo L, Liu L . Virtual touch tissue quantification of acoustic radiation force impulse: a new ultrasound elastic imaging in the diagnosis of thyroid nodules. PLoS One. 2012; 7(11):e49094. PMC: 3496737. DOI: 10.1371/journal.pone.0049094. View

Yang J, Schnadig V, Logrono R, Wasserman P . Fine-needle aspiration of thyroid nodules: a study of 4703 patients with histologic and clinical correlations. Cancer. 2007; 111(5):306-15. DOI: 10.1002/cncr.22955. View

Chow L, Gharib H, Goellner J, Van Heerden J . Nondiagnostic thyroid fine-needle aspiration cytology: management dilemmas. Thyroid. 2002; 11(12):1147-51. DOI: 10.1089/10507250152740993. View

Dighe M, Bae U, Richardson M, Dubinsky T, Minoshima S, Kim Y . Differential diagnosis of thyroid nodules with US elastography using carotid artery pulsation. Radiology. 2008; 248(2):662-9. DOI: 10.1148/radiol.2482071758. View

Tranquart F, Bleuzen A, Pierre-Renoult P, Chabrolle C, Sam Giao M, Lecomte P . [Elastosonography of thyroid lesions]. J Radiol. 2008; 89(1 Pt 1):35-9. DOI: 10.1016/s0221-0363(08)70367-6. View

Teng D, Wang H, Lin Y, Sui G, Guo F, Sun L . Value of ultrasound elastography in assessment of enlarged cervical lymph nodes. Asian Pac J Cancer Prev. 2012; 13(5):2081-5. DOI: 10.7314/apjcp.2012.13.5.2081. View

10.

Kagoya R, Monobe H, Tojima H . Utility of elastography for differential diagnosis of benign and malignant thyroid nodules. Otolaryngol Head Neck Surg. 2010; 143(2):230-4. DOI: 10.1016/j.otohns.2010.04.006. View

11.

Bhatia K, Cho C, Tong C, Lee Y, Yuen E, Ahuja A . Shear wave elastography of focal salivary gland lesions: preliminary experience in a routine head and neck US clinic. Eur Radiol. 2011; 22(5):957-65. DOI: 10.1007/s00330-011-2364-3. View

12.

Ning C, Jiang S, Zhang T, Sun L, Liu Y, Tian J . The value of strain ratio in differential diagnosis of thyroid solid nodules. Eur J Radiol. 2011; 81(2):286-91. DOI: 10.1016/j.ejrad.2010.12.010. View

13.

Dighe M, Kim J, Luo S, Kim Y . Utility of the ultrasound elastographic systolic thyroid stiffness index in reducing fine-needle aspirations. J Ultrasound Med. 2010; 29(4):565-74. DOI: 10.7863/jum.2010.29.4.565. View

14.

Lyshchik A, Higashi T, Asato R, Tanaka S, Ito J, Hiraoka M . Elastic moduli of thyroid tissues under compression. Ultrason Imaging. 2005; 27(2):101-10. DOI: 10.1177/016173460502700204. View

15.

Bojunga J, Herrmann E, Meyer G, Weber S, Zeuzem S, Friedrich-Rust M . Real-time elastography for the differentiation of benign and malignant thyroid nodules: a meta-analysis. Thyroid. 2010; 20(10):1145-50. DOI: 10.1089/thy.2010.0079. View

16.

Vorlander C, Wolff J, Saalabian S, Lienenluke R, Wahl R . Real-time ultrasound elastography--a noninvasive diagnostic procedure for evaluating dominant thyroid nodules. Langenbecks Arch Surg. 2010; 395(7):865-71. DOI: 10.1007/s00423-010-0685-3. View

17.

Wang Y, Dan H, Dan H, Li T, Hu B . Differential diagnosis of small single solid thyroid nodules using real-time ultrasound elastography. J Int Med Res. 2010; 38(2):466-72. DOI: 10.1177/147323001003800210. View

18.

Asteria C, Giovanardi A, Pizzocaro A, Cozzaglio L, Morabito A, Somalvico F . US-elastography in the differential diagnosis of benign and malignant thyroid nodules. Thyroid. 2008; 18(5):523-31. DOI: 10.1089/thy.2007.0323. View

19.

Klintworth N, Mantsopoulos K, Zenk J, Psychogios G, Iro H, Bozzato A . Sonoelastography of parotid gland tumours: initial experience and identification of characteristic patterns. Eur Radiol. 2012; 22(5):947-56. DOI: 10.1007/s00330-011-2344-7. View

20.

Cantisani V, Ulisse S, Guaitoli E, De Vito C, Caruso R, Mocini R . Q-elastography in the presurgical diagnosis of thyroid nodules with indeterminate cytology. PLoS One. 2012; 7(11):e50725. PMC: 3510167. DOI: 10.1371/journal.pone.0050725. View