Cellular Myxoma of the Lumbar Spine

Overview

Journal Surg Neurol Int

Specialty Neurology

Date 2013 Jul 23

PMID 23869282

Citations 5

Authors

Victoria Ohla

Pedro D S C Ciarlini

Jeffrey D Goldsmith

Ekkehard M Kasper

Affiliations

Soon will be listed here.

Abstract

Background: Cellular myxoma is a histopathologically distinctive benign neoplasm, which has often been categorized among the broad category of benign mesenchymal tumors with myxoid stroma and fibroblast- and/or myofibroblast-like cells. These tumors can arise in any of the large muscles and are usually found in the thigh, shoulder, buttocks, and upper arm, and more rarely in the head and neck or in small muscles of the hand.

Case Description: Here we illustrate the case of a 57-year-old female with a spinal lesion, who initially presented with complaints of vague pelvic discomfort but no focal neurological deficits. Imaging revealed a sharply demarcated paraspinal lesion concerning for a tumorous growth. The lesion was excised in toto and a detailed immuno-histopathological analysis was performed revealing the diagnosis of a cellular myxoma. Postoperative imaging showed a gross total resection and the patient is under clinical surveillance since, with no signs of recurrence after 42 months.

Conclusion: Although very rare, this entity should be considered in the differential diagnosis of any spinal and paraspinal mass to allow for adequate treatment, which requires wide excision with clean margins to avoid any local recurrence.

Citing Articles

Lumbar paraspinal intramuscular myxoma: A case report.

Hipolito-Reis J, Roque D, Teixeira J Surg Neurol Int. 2023; 14:86.

PMID: 37025538 PMC: 10070254. DOI: 10.25259/SNI_141_2023.

Spinal myxomas: review of a rare entity.

Patel S, Suji T, Pang G, Alg V, Visagan R, Reisz Z J Surg Case Rep. 2022; 2022(5):rjac221.

PMID: 35665391 PMC: 9156026. DOI: 10.1093/jscr/rjac221.

Surgical Treatment of Intramuscular Myxoma.

Sukpanichyingyong S, Matsumoto S, Ae K, Tanizawa T, Hayakawa K, Funauchi Y Indian J Orthop. 2021; 55(4):892-897.

PMID: 34194644 PMC: 8192669. DOI: 10.1007/s43465-021-00367-9.

Rare Hypothenar Myxoma Causing Ulnar Neuropathy: Histopathology and Treatment Pearls.

Firouzbakht P, Israel J, Christie B, Rao V Plast Reconstr Surg Glob Open. 2018; 6(7):e1806.

PMID: 30175009 PMC: 6110681. DOI: 10.1097/GOX.0000000000001806.

Atypical Intramuscular Myxoma of the Lumbosacral Paraspinal Muscle: The First Case Report in Asian.

Choi D, Kim J, Kim J, Lee H J Korean Neurosurg Soc. 2016; 58(6):566-70.

PMID: 26819696 PMC: 4728099. DOI: 10.3340/jkns.2015.58.6.566.

References

Shugar J, Som P, MEYERS R, Schaeffer B . Intramuscular head and neck myxoma: report of a case and review of the literature. Laryngoscope. 1987; 97(1):105-7. DOI: 10.1288/00005537-198701000-00021. View

Patsiaoura K, Anagnostou E, Benis N . Intramuscular myxoma of the nasal vestibule. Auris Nasus Larynx. 2009; 37(1):100-2. DOI: 10.1016/j.anl.2009.02.014. View

Al-Qattan M . Myxoma of the hand. J Hand Surg Br. 1996; 21(5):690-2. DOI: 10.1016/s0266-7681(96)80163-x. View

Logel R . Recurrent intramuscular myxoma associated with Albright's syndrome. J Bone Joint Surg Am. 1976; 58(4):565-8. View

Feldman P . A comparative study including ultrastructure of intramuscular myxoma and myxoid liposarcoma. Cancer. 1979; 43(2):512-25. DOI: 10.1002/1097-0142(197902)43:2<512::aid-cncr2820430217>3.0.co;2-h. View

Nielsen G, OConnell J, Rosenberg A . Intramuscular myxoma: a clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants. Am J Surg Pathol. 1998; 22(10):1222-7. DOI: 10.1097/00000478-199810000-00007. View

Aoki T, Kouho H, Hisaoka M, Hashimoto H, Nakata H, Sakai A . Intramuscular myxoma with fibrous dysplasia: a report of two cases with a review of the literature. Pathol Int. 1995; 45(2):165-71. DOI: 10.1111/j.1440-1827.1995.tb03438.x. View

Guppy K, Wagner F, Tawk R, Gallagher L . Intramuscular myxoma causing lumbar radiculopathy. Case report and review of the literature. J Neurosurg. 2001; 95(2 Suppl):260-3. DOI: 10.3171/spi.2001.95.2.0260. View

Liguoro D, Viejo-Fuertes D, Vital A, San Galli F, Dautheribes M, Guerin J . [Intramuscular myxoma. A case of myxoma of the spinal erector muscle]. Neurochirurgie. 1999; 45(1):54-7. View

10.

Caro P, Dubrana F, Le Nen D, Lefevre C, Courtois B . [Intramuscular myxoma. Apropos of a case and review of the literature]. Rev Chir Orthop Reparatrice Appar Mot. 1991; 77(8):568-70. View

11.

Taggarshe D, Raheja S, Yoo S, Mittal V . Intramuscular myxoma: a rare back mass. Am Surg. 2010; 76(11):1303-4. View

12.

Heymans O, Gebhart M, Alexiou J, De Saint Aubain N, Larsimont D . Intramuscular myxoma. Acta Chir Belg. 1998; 98(3):120-2. View

13.

Kamoun N, Zouari M, Siala M, Karray S, Douik M, Litaiem T . [Intramuscular myxoma. Apropos of two cases]. Rev Chir Orthop Reparatrice Appar Mot. 1997; 83(3):278-82. View

14.

Gaumetou E, Tomeno B, Anract P . Mazabraud's syndrome. A case with multiple myxomas. Orthop Traumatol Surg Res. 2012; 98(4):455-60. DOI: 10.1016/j.otsr.2012.04.002. View

15.

Murphey M, McRae G, Fanburg-Smith J, Temple H, Levine A, Aboulafia A . Imaging of soft-tissue myxoma with emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology. 2002; 225(1):215-24. DOI: 10.1148/radiol.2251011627. View

16.

Tahmouresie A, Farmer P, Stokes N . Paraspinal myxoma with spinal cord compression. Case report. J Neurosurg. 1981; 54(4):542-4. DOI: 10.3171/jns.1981.54.4.0542. View

17.

Allen P . Myxoma is not a single entity: a review of the concept of myxoma. Ann Diagn Pathol. 2000; 4(2):99-123. DOI: 10.1016/s1092-9134(00)90019-4. View

18.

Van Roggen J, McMenamin M, Fletcher C . Cellular myxoma of soft tissue: a clinicopathological study of 38 cases confirming indolent clinical behaviour. Histopathology. 2001; 39(3):287-97. DOI: 10.1046/j.1365-2559.2001.01209.x. View

19.

Crankson S, Al Namshan M, Al Mane K, Bamefleh H . Intramuscular myxoma: a rare neck mass in a child. Pediatr Radiol. 2002; 32(2):120-2. DOI: 10.1007/s00247-001-0603-5. View

20.

Bancroft L, Kransdorf M, Menke D, OConnor M, Foster W . Intramuscular myxoma: characteristic MR imaging features. AJR Am J Roentgenol. 2002; 178(5):1255-9. DOI: 10.2214/ajr.178.5.1781255. View