Glue Versus Suture Fixation of Mesh During Open Repair of Inguinal Hernias: a Systematic Review and Meta-analysis

Overview

Journal World J Surg

Publisher Wiley

Specialty General Surgery

Date 2013 Jul 23

PMID 23868471

Citations 21

Authors

Hugh Shunsuke Colvin

Ahsan Rao

Marta Cavali

Giampiero Campanelli

Amin Ibrahim Amin

Affiliations

Soon will be listed here.

Abstract

Background: Glue fixation of mesh has been explored for some time as a strategy for reducing postoperative chronic groin pain. Previous studies have come to different conclusions about the superiority of one method over another. We conducted a meta-analysis of randomized control trials comparing the performance of glue versus suture fixation of mesh in open inguinal hernioplasty.

Methods: Studies published up to November 2012 were searched using PubMed, EMBASE, MEDLINE, Cochrane Library, and the international standard randomised controlled trials number (ISRCTN) register. Mean differences (MDs) were derived from secondary continuous outcomes and pooled risk ratios (RRs) for categoric outcomes. Meta-analysis was conducted utilizing the random-effects and fixed-effects models as appropriate.

Results: Ten randomized controlled studies were selected, with a total of 1,623 patients. Glue fixation for open inguinal hernioplasty reduced chronic groin pain (RR 0.46, 95 % confidence interval (CI) 0.22-0.97), hematoma (RR 0.56, 95 % CI 0.34-0.90), acute postoperative pain (MD -7.92, 95 % CI, -13.17 to -2.66), and time taken to return to normal activities (MD -1.39, 95 % CI, -2.58 to -0.21). There was no evidence of an increase in adverse outcomes including recurrence with glue fixation (RR 0.83, 95 % CI 0.30-2.35).

Conclusions: Glue fixation of mesh for open inguinal hernioplasty is superior in many outcomes including the reduction of chronic groin pain. Glue fixation was not associated with an increased risk of hernia recurrence.

Citing Articles

comparison of mesh fixation solutions in open and laparoscopic procedures for inguinal hernia repair: A meta-analysis.

Giordano C, Rosellini E, Cascone M, Di Puccio F Heliyon. 2024; 10(7):e28711.

PMID: 38689996 PMC: 11059548. DOI: 10.1016/j.heliyon.2024.e28711.

Sutureless Repair for Open Treatment of Inguinal Hernia: Three Techniques in Comparison.

Baldini E, Lori E, Morini C, Palla L, Coletta D, De Luca G J Clin Med. 2024; 13(2).

PMID: 38276095 PMC: 10816828. DOI: 10.3390/jcm13020589.

Cyanoacrylate mesh fixation for laparoscopic inguinal hernia repair: a prospective, multicenter, single-arm study.

Dams A, Vankeirsbilck J, Poelmans S, Kerschaever I, Borreman P, Berwouts L Surg Endosc. 2023; 37(12):9105-9115.

PMID: 37798529 DOI: 10.1007/s00464-023-10439-6.

Cost-effectiveness analysis of mesh fixation techniques for laparoscopic and open inguinal hernia surgeries.

Techapongsatorn S, Tansawet A, Pattanaprateep O, Attia J, Mckay G, Thakkinstian A BMC Health Serv Res. 2022; 22(1):1125.

PMID: 36068521 PMC: 9450344. DOI: 10.1186/s12913-022-08491-4.

Mesh-fixation technique for inguinal hernia repair: umbrella review.

Techapongsatorn S, Tansawet A, Pattanaprateep O, Attia J, Mckay G, Thakkinstian A BJS Open. 2022; 6(4).

PMID: 35811449 PMC: 9271883. DOI: 10.1093/bjsopen/zrac084.

References

Nahabedian M, Dellon A . Outcome of the operative management of nerve injuries in the ilioinguinal region. J Am Coll Surg. 1997; 184(3):265-8. View

Moher D, Liberati A, Tetzlaff J, Altman D . Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009; 6(7):e1000097. PMC: 2707599. DOI: 10.1371/journal.pmed.1000097. View

Bay-Nielsen M, Perkins F, Kehlet H . Pain and functional impairment 1 year after inguinal herniorrhaphy: a nationwide questionnaire study. Ann Surg. 2001; 233(1):1-7. PMC: 1421158. DOI: 10.1097/00000658-200101000-00001. View

Katkhouda N, Mavor E, Friedlander M, Mason R, Kiyabu M, Grant S . Use of fibrin sealant for prosthetic mesh fixation in laparoscopic extraperitoneal inguinal hernia repair. Ann Surg. 2001; 233(1):18-25. PMC: 1421161. DOI: 10.1097/00000658-200101000-00004. View

Kim-Fuchs C, Angst E, Vorburger S, Helbling C, Candinas D, Schlumpf R . Prospective randomized trial comparing sutured with sutureless mesh fixation for Lichtenstein hernia repair: long-term results. Hernia. 2011; 16(1):21-7. DOI: 10.1007/s10029-011-0856-3. View

Callesen T, Bech K, Kehlet H . Prospective study of chronic pain after groin hernia repair. Br J Surg. 1999; 86(12):1528-31. DOI: 10.1046/j.1365-2168.1999.01320.x. View

Zieren J, CASTENHOLZ E, BAUMGART E, Muller J . Effects of fibrin glue and growth factors released from platelets on abdominal hernia repair with a resorbable PGA mesh: experimental study. J Surg Res. 1999; 85(2):267-72. DOI: 10.1006/jsre.1999.5608. View

Bruna Esteban M, Cantos Pallares M, Artigues Sanchez de Rojas E . [Use of adhesive mesh in hernioplasty compared to the conventional technique. Results of a randomised prospective study]. Cir Esp. 2010; 88(4):253-8. DOI: 10.1016/j.ciresp.2010.06.008. View

Kumar S, Wilson R, Nixon S, Macintyre I . Chronic pain after laparoscopic and open mesh repair of groin hernia. Br J Surg. 2002; 89(11):1476-9. DOI: 10.1046/j.1365-2168.2002.02260.x. View

10.

Testini M, Lissidini G, Poli E, Gurrado A, Lardo D, Piccinni G . A single-surgeon randomized trial comparing sutures, N-butyl-2-cyanoacrylate and human fibrin glue for mesh fixation during primary inguinal hernia repair. Can J Surg. 2010; 53(3):155-60. PMC: 2878998. View

11.

Nowobilski W, Dobosz M, Wojciechowicz T, Mionskowska L . Lichtenstein inguinal hernioplasty using butyl-2-cyanoacrylate versus sutures. Preliminary experience of a prospective randomized trial. Eur Surg Res. 2004; 36(6):367-70. DOI: 10.1159/000081646. View

12.

Eldabe Mikhail A, Palomo Luquero A, Pascual J, Seco Gil J . [Prosthetic material fixation in open inguinal hernioplasty: suture vs. synthetic glue]. Cir Esp. 2012; 90(7):446-52. DOI: 10.1016/j.ciresp.2012.05.003. View

13.

Torcivia A, Vons C, Barrat C, Dufour F, Champault G . Influence of mesh type on the quality of early outcomes after inguinal hernia repair in ambulatory setting controlled study: Glucamesh® vs Polypropylene®. Langenbecks Arch Surg. 2010; 396(2):173-8. DOI: 10.1007/s00423-010-0722-2. View

14.

OReilly E, Burke J, OConnell P . A meta-analysis of surgical morbidity and recurrence after laparoscopic and open repair of primary unilateral inguinal hernia. Ann Surg. 2012; 255(5):846-53. DOI: 10.1097/SLA.0b013e31824e96cf. View

15.

Nienhuijs S, Staal E, Strobbe L, Rosman C, Groenewoud H, Bleichrodt R . Chronic pain after mesh repair of inguinal hernia: a systematic review. Am J Surg. 2007; 194(3):394-400. DOI: 10.1016/j.amjsurg.2007.02.012. View

16.

Jadad A, Moore R, Carroll D, Jenkinson C, Reynolds D, Gavaghan D . Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials. 1996; 17(1):1-12. DOI: 10.1016/0197-2456(95)00134-4. View

17.

Campanelli G, Pascual M, Hoeferlin A, Rosenberg J, Champault G, Kingsnorth A . Randomized, controlled, blinded trial of Tisseel/Tissucol for mesh fixation in patients undergoing Lichtenstein technique for primary inguinal hernia repair: results of the TIMELI trial. Ann Surg. 2012; 255(4):650-7. DOI: 10.1097/SLA.0b013e31824b32bf. View

18.

Sajid M, Leaver C, Baig M, Sains P . Systematic review and meta-analysis of the use of lightweight versus heavyweight mesh in open inguinal hernia repair. Br J Surg. 2011; 99(1):29-37. DOI: 10.1002/bjs.7718. View

19.

Kaul A, Hutfless S, Le H, Hamed S, Tymitz K, Nguyen H . Staple versus fibrin glue fixation in laparoscopic total extraperitoneal repair of inguinal hernia: a systematic review and meta-analysis. Surg Endosc. 2012; 26(5):1269-78. DOI: 10.1007/s00464-011-2025-2. View

20.

Pierides G, Scheinin T, Remes V, Hermunen K, Vironen J . Randomized comparison of self-fixating and sutured mesh in open inguinal hernia repair. Br J Surg. 2012; 99(5):630-6. DOI: 10.1002/bjs.8705. View