Management of Neurogenic Orthostatic Hypotension in Patients with Autonomic Failure

Overview

Journal Drugs

Specialty Pharmacology

Date 2013 Jul 17

PMID 23857549

Citations 14

Authors

Christoph Schroeder

Jens Jordan

Horacio Kaufmann

Affiliations

Soon will be listed here.

Abstract

The maintenance of blood pressure in the upright position requires intact autonomic cardiovascular reflexes. Diseases that affect the sympathetic innervation of the cardiovascular system result in a sustained fall in blood pressure upon standing (i.e., neurogenic orthostatic hypotension) that can impair the blood supply to the brain and other organs and cause considerable morbidity and mortality. Here we review treatment options for neurogenic orthostatic hypotension and include an algorithm for its management that emphasizes the importance of non-pharmacologic measures and provides guidance on pharmacologic treatment options.

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