Prevalence and Risk Factors of Posterior Vitreous Detachment in a Chinese Adult Population: the Handan Eye Study

Overview

Journal BMC Ophthalmol

Publisher Biomed Central

Specialty Ophthalmology

Date 2013 Jul 17

PMID 23855829

Citations 10

Authors

Zhijun Shen

Xinrong Duan

Fenghua Wang

Ningli Wang

Yi Peng

David T L Liu

Xiaoyan Peng

Sizhen Li

Yuanbo Liang

Affiliations

Soon will be listed here.

Abstract

Background: To describe the prevalence and associations of posterior vitreous detachment (PVD) in a rural adult Chinese population.

Methods: All eligible subjects were requested to carry out a comprehensive eye examination; PVD was a pre-specified outcome variable and was determined via biomicroscopical examination (slit-lamp biomicroscopy) with a +90-D preset lens after mydriasis. Prevalence was standardized to China population census (2000).

Results: 5890 (86.2%) subjects completed the examination of slit-lamp biomicroscopy with a +90-D lens. PVD was present in 160 participants (2.7%); the standardized prevalence was 2.0% (95% confidence interval [CI], 1.6-2.3%). PVD developed increasingly with age (P for trend < 0.001) for both men and women. Using a multivariate regression model, older people were found to run a higher risk of developing PVD than younger people, and women were found to have a higher risk than men (OR, 2.9; 95% CI, 1.5-5.9). Diabetes, hypertension, smoking, drinking, and intraocular pressure (IOP) were not significantly associated with PVD.

Conclusions: About one in fifty people is found to have PVD in this population-based study. Age and female are independently associated with PVD occurrence.

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