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Preemptive Analgesia in Third Molar Impaction Surgery

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Date 2013 Jul 9
PMID 23833488
Citations 11
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Abstract

Introduction: We have evaluated efficacy of diclofenac sodium as pre-emptive analgesia agent in a prospective triple blind placebo controlled randomized clinical trial in a patients undergoing third molar impaction surgery.

Materials And Methods: Randomization of groups was done by randomization software and two groups were constituted one group receiving placebo pre operatively and then the drug for next five days while the other group was given diclofenac sodium pre operatively and then for five days.

Results: Results were achieved with help of measurement of outcome variables like postoperative tenderness, swelling and trismus on a visual analogous scale (VAS) and other personalized scale. Collected data shows that there is a significant reduction in the score of postop tenderness in experimental group (P = 0.00), while there is a minimal difference between score of postoperative swelling and tenderness (P > 0.04).

Conclusion: So, we can conclude that use of diclofenac sodium as a preemptive analgesic agent is beneficial for better pain control in third molar impaction surgery.

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References
1.
Kelly D, Ahmad M, Brull S . Preemptive analgesia I: physiological pathways and pharmacological modalities. Can J Anaesth. 2001; 48(10):1000-10. DOI: 10.1007/BF03016591. View

2.
Kaczmarzyk T, Wichlinski J, Stypulkowska J, Zaleska M, Woron J . Preemptive effect of ketoprofen on postoperative pain following third molar surgery. A prospective, randomized, double-blinded clinical trial. Int J Oral Maxillofac Surg. 2010; 39(7):647-52. DOI: 10.1016/j.ijom.2010.02.019. View

3.
Pozos-Guillen A, Martinez-Rider R, Aguirre-Banuelos P, Perez-Urizar J . Pre-emptive analgesic effect of tramadol after mandibular third molar extraction: a pilot study. J Oral Maxillofac Surg. 2007; 65(7):1315-20. DOI: 10.1016/j.joms.2006.10.079. View

4.
Pektas Z, Sener M, Bayram B, Eroglu T, Bozdogan N, Donmez A . A comparison of pre-emptive analgesic efficacy of diflunisal and lornoxicam for postoperative pain management: a prospective, randomized, single-blind, crossover study. Int J Oral Maxillofac Surg. 2006; 36(2):123-7. DOI: 10.1016/j.ijom.2006.10.005. View

5.
Ong K, Tan J . Preoperative intravenous tramadol versus ketorolac for preventing postoperative pain after third molar surgery. Int J Oral Maxillofac Surg. 2004; 33(3):274-8. DOI: 10.1006/ijom.2003.0515. View