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Concentrations of Cefixime in Bronchial Mucosa and Sputum After Three Oral Multiple Dose Regimens

Overview
Journal Thorax
Date 1990 May 1
PMID 2382246
Citations 7
Authors
D R Baldwin
J M Andrews
J P Ashby
R Wise
D Honeybourne
Affiliations
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Abstract

In a study of 58 patients the concentrations of cefixime, a new oral cephem antibiotic, in bronchial mucosa were 35-40% of the concentrations found in simultaneously collected serum samples. The antibiotic was often undetectable in sputum despite a highly sensitive assay.

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