Intracranial Metastasis of Neuroblastoma: in Two Different Areas at the Same Time

Overview

Journal Childs Nerv Syst

Specialty Pediatrics

Date 2013 Jun 25

PMID 23793924

Citations 1

Authors

Dogan Kose

Pinar Karabagli

Guler Yavas

Hakan Karabagli

Yavuz Koksal

Affiliations

Soon will be listed here.

Abstract

Introduction: Neuroblastoma (NB) is the most common extracranial solid malignancy in children. The major cause of death from this cancer is metastasis of tumors, and metastasis can be seen in different areas of the body. Metastasis of NB occurs by hematogenous and lymphatic routes. Generally, brain metastases have been reported in only one area of the brain parenchyma.

Case Report: A 4-year-old male patient was treated in our clinic due to the NB that settled in the intra-abdominal region, but the patient presented with headache and nausea approximately 5 months after completion of the treatment. Whereupon, cranial imaging was performed and two masses were detected in the bilateral frontal lobe, and then the patient underwent surgery. Metastatic NB diagnosis was confirmed histopathologically. The patient's chemotherapy treatment is still ongoing.

Conclusion: We report the case of a male patient with two separate metastatic masses in the brain parenchyma, which occurred in two different areas at the same time.

Citing Articles

Intracranial Metastases Tend to Be Overt and Predict Poor Prognosis in Children With Neuroblastoma.

Huo L, Zhang J, Liu Y Front Pediatr. 2021; 9:716880.

PMID: 34805033 PMC: 8596640. DOI: 10.3389/fped.2021.716880.

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