A Novel Nanometric DNA Thin Film As a Sensor for Alpha Radiation

Overview

Journal Sci Rep

Specialty Science

Date 2013 Jun 25

PMID 23792924

Citations 7

Authors

Atul Kulkarni

Byeonghoon Kim

Sreekantha Reddy Dugasani

Pranav Joshirao

Jang Ah Kim

Chirag Vyas

Vijay Manchanda

Taesung Kim

Sung Ha Park

Affiliations

Soon will be listed here.

Abstract

The unexpected nuclear accidents have provided a challenge for scientists and engineers to develop sensitive detectors, especially for alpha radiation. Due to the high linear energy transfer value, sensors designed to detect such radiation require placement in close proximity to the radiation source. Here we report the morphological changes and optical responses of artificially designed DNA thin films in response to exposure to alpha radiation as observed by an atomic force microscope, a Raman and a reflectance spectroscopes. In addition, we discuss the feasibility of a DNA thin film as a radiation sensing material. The effect of alpha radiation exposure on the DNA thin film was evaluated as a function of distance from an ²⁴¹Am source and exposure time. Significant reflected intensity changes of the exposed DNA thin film suggest that a thin film made of biomolecules can be one of promising candidates for the development of online radiation sensors.

Citing Articles

Dual-band transparency over near-IR and THz in surfactant-free DNA solid film.

Jeong H, Cheona S, Lee Y, Ghasemi M, Kim S, Kang C Sci Rep. 2024; 14(1):28811.

PMID: 39567517 PMC: 11579397. DOI: 10.1038/s41598-024-77968-5.

Linear and nonlinear optical properties of transfer ribonucleic acid (tRNA) thin solid films.

Ghasemi M, Jeong H, Kim D, Kim B, Jang J, Oh K RSC Adv. 2022; 12(14):8661-8667.

PMID: 35424810 PMC: 8984844. DOI: 10.1039/d1ra09412b.

Protein phosphatase 2A inhibition enhances radiation sensitivity and reduces tumor growth in chordoma.

Hao S, Song H, Zhang W, Seldomridge A, Jung J, Giles A Neuro Oncol. 2018; 20(6):799-809.

PMID: 29294092 PMC: 5961117. DOI: 10.1093/neuonc/nox241.

Ultra-low Doping on Two-Dimensional Transition Metal Dichalcogenides using DNA Nanostructure Doped by a Combination of Lanthanide and Metal Ions.

Kang D, Dugasani S, Park H, Shim J, Gnapareddy B, Jeon J Sci Rep. 2016; 6:20333.

PMID: 26838524 PMC: 4738262. DOI: 10.1038/srep20333.

Electronic Characterization of Au/DNA/ITO Metal-Semiconductor-Metal Diode and Its Application as a Radiation Sensor.

Al-Taii H, Periasamy V, Amin Y PLoS One. 2016; 11(1):e0145423.

PMID: 26799703 PMC: 4723132. DOI: 10.1371/journal.pone.0145423.

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