Juxta-articular Large Cell Lymphoma
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Three patients with juxta-articular large cell lymphoma presented as suffering from monarthropathies. A spectrum of radiographic changes was observed that included subchondral sclerosis, regional osteopenia, effusion, and mottled lytic changes in the juxta-articular region of the affected joint. MRI was performed in two patients. In one, it revealed a high signal mass on T2-weighted sequences. In the second, a mass bridging the joint was demonstrated which was difficult to appreciate on CT and was not visible radiographically. In all cases, biopsies revealed large cell non-Hodgkin's lymphoma of bone. We present these studies to emphasize this unusual pattern of non-Hodgkin's lymphoma as well as to demonstrate the contribution of MRI to the diagnosis.
Case report 764. Primary lymphoma of bone, large cell, B-phenotype with articular involvement.
Beatty P, Bjorkengren A, Moore S, Gelb A, Gamble J Skeletal Radiol. 1992; 21(8):559-61.
PMID: 1465654 DOI: 10.1007/BF00195244.