Real-time PCR As a Prognostic Tool for Human Congenital Toxoplasmosis

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 2013 Jun 14

PMID 23761154

Citations 9

Authors

Julia Gatti Ladeia Costa

Ana Carolina Aguiar Vasconcelos Carneiro

Alice Thomaz Tavares

Glaucia Manzan Queiroz Andrade

Daniel Vitor Vasconcelos-Santos

Jose Nelio Januario

Daniel Menezes-Souza

Ricardo Toshio Fujiwara

Ricardo Wagner Almeida Vitor

Affiliations

Soon will be listed here.

Abstract

Real-time PCR (qPCR) was positive in 72/150 (48%) blood samples of newborns with congenital toxoplasmosis. Among infants with active retinochoroiditis, 68% had positive qPCR results, while positivity was 29% (P=0.009) in the absence of ocular involvement. Positive qPCR was associated with the presence of retinochoroidal lesions, with an odds ratio of 2.8.

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