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» Articles » PMID: 23730072

OraVerse: Reverses Numbness After Dental Procedures

Overview
Journal J Maxillofac Oral Surg
Date 2013 Jun 5
PMID 23730072
Citations 6
Authors
J S Prasanna
Affiliations
Soon will be listed here.
Abstract

The lingering numbness that can last anywhere from 3 to 5 h after a routine dental procedure is often an unnecessary, inconvenient hassle. Patients may find that their ability to speak, smile, eat and drink is impaired, and may even have uncontrollable drooling. The effects of local dental anesthetics can now be reversed. That's because OraVerse, an anesthetic reversal agent, can return the patient to normal sensation and function in about half the time. OraVerse which is U.S. Food and Drug Administration approved is a safe and effective form of phentolamine mesylate, a vasodilator that has been used in several other medical applications since 1952. OraVerse injection - the first and only proven safe and effective product of its kind can quickly reverse the effects of local dental anesthetics, so patient can carry on without impairment of talk, smile and drink after dental procedures. Studies also have shown that there are no known drug interactions and no evident toxicity or contraindications for using OraVerse.

Citing Articles

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Effect of Phentolamine as Reversal of Soft-Tissue Anesthesia on Post-Endodontic Pain in Patients with Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial.

Shadmehr E, Saatchi M, Damoon Sarmast N, Bagherieh S, Davoudi A Iran Endod J. 2023; 14(4):247-252.

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Use of Phentolamine Mesylate in Implant Surgery: Analysis of Adverse Effects and Haemodynamic Changes.

Vintanel-Moreno C, Martinez-Gonzalez J, Martinez-Rodriguez N, Meniz-Garcia C, Leco-Berrocal I J Clin Med. 2021; 10(17).

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Efficacy of phentolamine mesylate in reducing the duration of various local anesthetics.

Gago-Garcia A, Barrilero-Martin C, Alobera-Gracia M, Del Canto-Pingarron M, Seco-Calvo J J Dent Anesth Pain Med. 2021; 21(1):49-59.

PMID: 33585684 PMC: 7871185. DOI: 10.17245/jdapm.2021.21.1.49.

Basic pharmacology of local anaesthetics.

Taylor A, McLeod G BJA Educ. 2021; 20(2):34-41.

PMID: 33456928 PMC: 7808030. DOI: 10.1016/j.bjae.2019.10.002.

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