The WU-Minn Human Connectome Project: an Overview

Overview

Journal Neuroimage

Specialty Radiology

Date 2013 May 21

PMID 23684880

Citations 2249

Authors

David C Van Essen

Stephen M Smith

Deanna M Barch

Timothy E J Behrens

Essa Yacoub

Kamil Ugurbil

Affiliations

Soon will be listed here.

Abstract

The Human Connectome Project consortium led by Washington University, University of Minnesota, and Oxford University is undertaking a systematic effort to map macroscopic human brain circuits and their relationship to behavior in a large population of healthy adults. This overview article focuses on progress made during the first half of the 5-year project in refining the methods for data acquisition and analysis. Preliminary analyses based on a finalized set of acquisition and preprocessing protocols demonstrate the exceptionally high quality of the data from each modality. The first quarterly release of imaging and behavioral data via the ConnectomeDB database demonstrates the commitment to making HCP datasets freely accessible. Altogether, the progress to date provides grounds for optimism that the HCP datasets and associated methods and software will become increasingly valuable resources for characterizing human brain connectivity and function, their relationship to behavior, and their heritability and genetic underpinnings.

Citing Articles

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Wang Y, Li S, He J, Peng L, Wang Q, Zou X Imaging Neurosci (Camb). 2025; 3.

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Neuroimaging changes in major depression with brief computer-assisted cognitive behavioral therapy compared to waitlist.

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