Sexual Dysfunction in Male Iraq and Afghanistan War Veterans: Association with Posttraumatic Stress Disorder and Other Combat-related Mental Health Disorders: a Population-based Cohort Study

Overview

Journal J Sex Med

Publisher Oxford University Press

Specialties Gynecology & Obstetrics
Reproductive Medicine
Urology

Date 2013 May 18

PMID 23679562

Citations 13

Authors

Benjamin N Breyer

Beth E Cohen

Daniel Bertenthal

Raymond C Rosen

Thomas C Neylan

Karen H Seal

Affiliations

Soon will be listed here.

Abstract

Introduction: Mental health disorders are prevalent in the United States, Iraq, and Afghanistan war veterans. Mental illness, including posttraumatic stress disorder (PTSD) with or without psychiatric medications, can increase the risk for male sexual dysfunction, threatening quality of life.

Aims: We sought to determine the prevalence and correlates of sexual dysfunction among male Iraq and Afghanistan veterans.

Methods: We performed a retrospective cohort study of 405,275 male Iraq and Afghanistan veterans who were new users of U.S. Department of Veterans Affairs healthcare from October 7, 2001 to September 30, 2009 and had 2-year follow-up.

Main Outcome Measures: We determined the independent association of mental health diagnoses and sexual dysfunction after adjusting for sociodemographic and military service characteristics, comorbidities, and medications.

Results: Veterans with PTSD were more likely to have a sexual dysfunction diagnosis, be prescribed medications for sexual dysfunction, or both (10.6%), compared with veterans having a mental diagnosis other than PTSD (7.2%), or no mental health diagnosis (2.3%). In a fully adjusted model, PTSD increased the risk of sexual dysfunction by more than threefold (adjusted risk ratio = 3.61, 95% CI = 3.48-3.75). Veterans with mental health disorders, particularly PTSD, were at the highest risk of sexual dysfunction when prescribed psychiatric medications (adjusted risk ratio = 4.59, 95% CI = 4.41-4.77).

Conclusions: Among U.S. combat veterans, mental health disorders, particularly PTSD, increased the risk of sexual dysfunction independent of the use of psychiatric medications.

Citing Articles

Sexual Health Assessment Is Vital to Whole Health Models of Care.

Uzdavines A, Helmer D, Spelman J, Mattocks K, Johnson A, Chardos J JMIRx Med. 2023; 3(3):e36266.

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Sexual Dysfunctions among Veterans with and without PTSD.

Protuder M, Stevanovic A, Letica-Crepulja M Healthcare (Basel). 2023; 11(13).

PMID: 37444696 PMC: 10340479. DOI: 10.3390/healthcare11131861.

Relationship Between Posttraumatic Stress Disorder and Sexual Difficulties: A Systematic Review of Veterans and Military Personnel.

Bird E, Piccirillo M, Garcia N, Blais R, Campbell S J Sex Med. 2021; 18(8):1398-1426.

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Saikosaponin D Rescues Deficits in Sexual Behavior and Ameliorates Neurological Dysfunction in Mice Exposed to Chronic Mild Stress.

Wang Z, Li J, Wu W, Qi T, Huang Z, Wang B Front Pharmacol. 2021; 12:625074.

PMID: 33776766 PMC: 7990100. DOI: 10.3389/fphar.2021.625074.

Erectile dysfunction in patients with anxiety disorders: a systematic review.

Velurajah R, Brunckhorst O, Waqar M, McMullen I, Ahmed K Int J Impot Res. 2021; 34(2):177-186.

PMID: 33603242 PMC: 8964411. DOI: 10.1038/s41443-020-00405-4.

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