Exhaustion of Racing Sperm in Nature-mimicking Microfluidic Channels During Sorting

Overview

Journal Small

Date 2013 May 17

PMID 23677651

Citations 42

Authors

Savas Tasoglu

Hooman Safaee

Xiaohui Zhang

James L Kingsley

Paolo N Catalano

Umut Atakan Gurkan

Aida Nureddin

Emre Kayaalp

Raymond M Anchan

Richard L Maas

Erkan Tuzel

Utkan Demirci

Affiliations

Soon will be listed here.

Abstract

Fertilization is central to the survival and propagation of a species, however, the precise mechanisms that regulate the sperm's journey to the egg are not well understood. In nature, the sperm has to swim through the cervical mucus, akin to a microfluidic channel. Inspired by this, a simple, cost-effective microfluidic channel is designed on the same scale. The experimental results are supported by a computational model incorporating the exhaustion time of sperm.

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