Being Unaware of Being HIV-infected is Associated with Alcohol Use Disorders and High-risk Sexual Behaviors Among Men Who Have Sex with Men in Peru

Overview

Journal AIDS Behav

Specialty Infectious Diseases

Date 2013 May 15

PMID 23670711

Citations 31

Authors

Panagiotis Vagenas

Kaysia T Ludford

Pedro Gonzales

Jesus Peinado

Cesar Cabezas

Fernando Gonzales

Javier R Lama

Jorge Sanchez

Frederick L Altice

Affiliations

Soon will be listed here.

Abstract

This study compared the correlates of HIV risk among men who have sex with men (MSM) with newly diagnosed versus previously known HIV infection among 5,148 MSM recruited using modified snowball sampling in 5 Peruvian cities. Participants, if age ≥18 years and reporting sex with a male in the previous 12 months, underwent standardized computer-assisted risk assessments and HIV and syphilis testing. Overall, 420 (8.2 %) participants tested HIV seropositive, most of whom (89.8 %) were unaware of their HIV status. Compared to those who knew themselves to be HIV-infected, multivariate logistic regression demonstrated that unprotected anal intercourse at last encounter [AOR = 2.84 (95 % CI 1.09-7.40)] and having an alcohol use disorder (AUD) [AOR = 2.14 (95 % CI 1.01-5.54)] were independently associated with a newly diagnosed HIV infection. Being unaware of being HIV-infected was associated with high-risk sexual behaviors and AUDs, both of which are amenable to behavioral and medication-assisted therapy interventions.

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References

Anton R, OMalley S, Ciraulo D, Cisler R, Couper D, Donovan D . Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA. 2006; 295(17):2003-17. DOI: 10.1001/jama.295.17.2003. View

van Griensven F, van Wijngaarden J, Baral S, Grulich A . The global epidemic of HIV infection among men who have sex with men. Curr Opin HIV AIDS. 2009; 4(4):300-7. DOI: 10.1097/COH.0b013e32832c3bb3. View

Blas M, Alva I, Cabello R, Carcamo C, Kurth A . Risk behaviors and reasons for not getting tested for HIV among men who have sex with men: an online survey in Peru. PLoS One. 2011; 6(11):e27334. PMC: 3212560. DOI: 10.1371/journal.pone.0027334. View

Granich R, Gilks C, Dye C, De Cock K, Williams B . Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet. 2008; 373(9657):48-57. DOI: 10.1016/S0140-6736(08)61697-9. View

Pedrana A, Hellard M, Wilson K, Guy R, Stoove M . High rates of undiagnosed HIV infections in a community sample of gay men in Melbourne, Australia. J Acquir Immune Defic Syndr. 2011; 59(1):94-9. DOI: 10.1097/QAI.0b013e3182396869. View

Cohen M, Chen Y, McCauley M, Gamble T, Hosseinipour M, Kumarasamy N . Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011; 365(6):493-505. PMC: 3200068. DOI: 10.1056/NEJMoa1105243. View

Binford M, Kahana S, Altice F . A systematic review of antiretroviral adherence interventions for HIV-infected people who use drugs. Curr HIV/AIDS Rep. 2012; 9(4):287-312. PMC: 3495269. DOI: 10.1007/s11904-012-0134-8. View

Kalichman S, Simbayi L, Kaufman M, Cain D, Jooste S . Alcohol use and sexual risks for HIV/AIDS in sub-Saharan Africa: systematic review of empirical findings. Prev Sci. 2007; 8(2):141-51. DOI: 10.1007/s11121-006-0061-2. View

. HIV testing among men who have sex with men--21 cities, United States, 2008. MMWR Morb Mortal Wkly Rep. 2011; 60(21):694-9. View

10.

Leigh B, Stall R . Substance use and risky sexual behavior for exposure to HIV. Issues in methodology, interpretation, and prevention. Am Psychol. 1993; 48(10):1035-45. PMC: 2585544. DOI: 10.1037//0003-066x.48.10.1035. View

11.

Workowski K, Berman S . Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep. 2006; 55(RR-11):1-94. View

12.

Charlebois E, Das M, Porco T, Havlir D . The effect of expanded antiretroviral treatment strategies on the HIV epidemic among men who have sex with men in San Francisco. Clin Infect Dis. 2011; 52(8):1046-9. PMC: 3070031. DOI: 10.1093/cid/cir085. View

13.

Lama J, Lucchetti A, Suarez L, Laguna-Torres V, Guanira J, Pun M . Association of herpes simplex virus type 2 infection and syphilis with human immunodeficiency virus infection among men who have sex with men in Peru. J Infect Dis. 2006; 194(10):1459-66. DOI: 10.1086/508548. View

14.

Garcia P, Holmes K, Carcamo C, Garnett G, Hughes J, Campos P . Prevention of sexually transmitted infections in urban communities (Peru PREVEN): a multicomponent community-randomised controlled trial. Lancet. 2012; 379(9821):1120-8. PMC: 3315635. DOI: 10.1016/S0140-6736(11)61846-1. View

15.

Grant R, Lama J, Anderson P, McMahan V, Liu A, Vargas L . Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010; 363(27):2587-99. PMC: 3079639. DOI: 10.1056/NEJMoa1011205. View

16.

Heath J, Lanoye A, Maisto S . The role of alcohol and substance use in risky sexual behavior among older men who have sex with men: a review and critique of the current literature. AIDS Behav. 2011; 16(3):578-89. PMC: 3743230. DOI: 10.1007/s10461-011-9921-2. View

17.

Sanchez J, Lama J, Kusunoki L, Manrique H, Goicochea P, Lucchetti A . HIV-1, sexually transmitted infections, and sexual behavior trends among men who have sex with men in Lima, Peru. J Acquir Immune Defic Syndr. 2007; 44(5):578-85. DOI: 10.1097/QAI.0b013e318033ff82. View

18.

Altice F, Kamarulzaman A, Soriano V, Schechter M, Friedland G . Treatment of medical, psychiatric, and substance-use comorbidities in people infected with HIV who use drugs. Lancet. 2010; 376(9738):367-87. PMC: 4855280. DOI: 10.1016/S0140-6736(10)60829-X. View

19.

Sanchez J, Lama J, Peinado J, Paredes A, Lucchetti A, Russell K . High HIV and ulcerative sexually transmitted infection incidence estimates among men who have sex with men in Peru: awaiting for an effective preventive intervention. J Acquir Immune Defic Syndr. 2009; 51 Suppl 1:S47-51. PMC: 2725017. DOI: 10.1097/QAI.0b013e3181a2671d. View

20.

Samet J, Mulvey K, Zaremba N, Plough A . HIV testing in substance abusers. Am J Drug Alcohol Abuse. 1999; 25(2):269-80. DOI: 10.1081/ada-100101860. View