» Articles » PMID: 23670249

Childhood Basilar Artery Occlusion: a Report of 5 Cases and Review of the Literature

Overview
Journal J Child Neurol
Specialties Neurology
Pediatrics
Date 2013 May 15
PMID 23670249
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Basilar artery occlusion has poor outcome in adults; little is known regarding outcomes in children. Whether intra-arterial treatments improve adult outcomes is controversial. Safety and efficacy of intra-arterial treatments in children are unknown. We report 5 cases of basilar artery occlusion and review published cases. We estimated National Institute of Health Stroke Scale (NIHSS) and modified Rankin Score (mRS) of published cases, compared scores between non-intra-arterial treatments and intra-arterial treatments groups, and examined the correlation between NIHSS and mRS. Of our cases, 4 had good outcomes and 1 died. Of 63 published cases, 45 had no intra-arterial treatments and 18 had intra-arterial treatments. In the non-intra-arterial treatments group 24 had good outcomes. In the intra-arterial treatments group 13 had good outcomes. There was strong correlation between the NIHSS and the mRS. Children with basilar artery occlusion have better outcomes than adults. Certain children with basilar artery occlusion may be treated conservatively. A registry for childhood basilar artery occlusion is urgently needed.

Citing Articles

Childhood acute basilar artery thrombosis successfully treated with mechanical thrombectomy using stent retrievers: case report and review of the literature.

Nicosia G, Cicala D, Mirone G, Spennato P, Trischitta V, Ruggiero C Childs Nerv Syst. 2016; 33(2):349-355.

PMID: 27704247 DOI: 10.1007/s00381-016-3259-z.

References
1.
Mattle H, Arnold M, Lindsberg P, Schonewille W, Schroth G . Basilar artery occlusion. Lancet Neurol. 2011; 10(11):1002-14. DOI: 10.1016/S1474-4422(11)70229-0. View

2.
Fowler M . Two cases of basilar artery occlusion in childhood. Arch Dis Child. 1962; 37:78-81. PMC: 2018872. DOI: 10.1136/adc.37.191.78. View

3.
Loevner L, Ting T, Hurst R, GOLDBERG H, Schut L . Spontaneous thrombosis of a basilar artery traumatic aneurysm in a child. AJNR Am J Neuroradiol. 1998; 19(2):386-8. PMC: 8338178. View

4.
Vergouwen M, Algra A, Pfefferkorn T, Weimar C, Rueckert C, Thijs V . Time is brain(stem) in basilar artery occlusion. Stroke. 2012; 43(11):3003-6. DOI: 10.1161/STROKEAHA.112.666867. View

5.
Fink J, Sonnenborg L, Larsen L, Born A, Holtmannspotter M, Kondziella D . Basilar Artery Thrombosis in a Child Treated With Intravenous Tissue Plasminogen Activator and Endovascular Mechanical Thrombectomy. J Child Neurol. 2012; 28(11):1521-1526. DOI: 10.1177/0883073812460334. View