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Acute Splenic Sequestration in a Pregnant Woman with Homozygous Sickle-cell Anemia

Overview
Journal Sao Paulo Med J
Specialty General Medicine
Date 2013 May 10
PMID 23657515
Citations 3
Authors
Carolina Bastos Maia
Roseli Mieko Yamamoto Nomura
Ana Maria Kondo Igai
Guilherme Hencklain Fonseca
Sandra Menosi Gualandro
Marcelo Zugaib
Affiliations
Soon will be listed here.
Abstract

Context: Homozygous (SS) sickle-cell anemia complicated by acute splenic sequestration in adults is a rare event, and it has never been reported during pregnancy.

Case Report: A 25-year-old woman with homozygous (SS) sickle-cell disease was hospitalized at 32 weeks' of gestation presenting weakness, abdominal pain, fever and hemoglobin of 2.4 g/dl. Abnormal fetal heart rate was detected by means of cardiotocography, and 5 units of packed red cells were transfused. Cesarean was performed at 37 weeks. Both mother and baby were discharged in a good general condition.

Conclusion: This case report demonstrates the importance of immediate blood transfusion for treatment of fetal distress in cases of splenic sequestration during pregnancy. This treatment is essential for avoiding maternal and fetal complications.

Citing Articles

Rescue splenic artery embolization in an adult patient of sickle cell disease presented with acute splenic sequestration crisis.

Mohapatra S, Das P, Rao P, Nayak M, Mane K, Sahoo B Emerg Radiol. 2024; 31(4):613-617.

PMID: 38797776 DOI: 10.1007/s10140-024-02246-w.

Adverse outcome of acute splenic sequestration crisis in pregnancy.

Malinowski A, Parrish J, DSouza R, Kuo K, Ward R, Shehata N Obstet Med. 2021; 14(2):113-115.

PMID: 34394722 PMC: 8358239. DOI: 10.1177/1753495X20936902.

Interleukin-6 in pregnancy with sickle cell disease.

Costa M, Torres L, Matta M, Araujo A, Souza A Hematol Transfus Cell Ther. 2019; 41(4):298-302.

PMID: 31133499 PMC: 6978540. DOI: 10.1016/j.htct.2019.02.001.

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