Triggers for Autism: Genetic and Environmental Factors

Overview

Journal J Cent Nerv Syst Dis

Publisher Sage Publications

Date 2013 May 8

PMID 23650465

Citations 4

Authors

Hideo Matsuzaki

Keiko Iwata

Takayuki Manabe

Norio Mori

Affiliations

Soon will be listed here.

Abstract

This report reviews the research on the factors that cause autism. In several studies, these factors have been verified by reproducing them in autistic animal models. Clinical research has demonstrated that genetic and environmental factors play a major role in the development of autism. However, most cases are idiopathic, and no single factor can explain the trends in the pathology and prevalence of autism. At the time of this writing, autism is viewed more as a multi-factorial disorder. However, the existence of an unknown factor that may be common in all autistic cases cannot be ruled out. It is hoped that future biological studies of autism will help construct a new theory that can interpret the pathology of autism in a coherent manner. To achieve this, large-scale epidemiological research is essential.

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