A Retrospective Audit of 200 Cases of CNS Tumours and Their Surgical Management in a Tertiary Care Centre

Overview

Journal Ir J Med Sci

Specialty General Medicine

Date 2013 May 7

PMID 23645548

Authors

F E Muhamat Nor

K Chandrasekaran

J C Marks

Affiliations

Soon will be listed here.

Abstract

Aims: To study the nature of the tumours managed in the Irish population.

Methods: This audit research was completed via a retrospective medical review on 200 patients with CNS tumours managed in a tertiary care centre between 2008 and 2009.

Results: The mean age was 53 years. The male:female ratio was 2:1. The majority were glioblastomas and astrocytomas. Grade IV tumours were predominant (65.5 %). Headaches (37 %), motor weakness (32 %) and seizures (25.5 %) were the highest presentations. The commonest sites affected were the left parietal and left temporal lobes. There were 17.5 % operative morbidities with motor weakness (22.9 %), seizure (14.3 %) and thrombo-embolism (14.3 %) dominating and significant association to surgical radicality (p = 0.041). 3.5 % operative mortalities were reported. 52.5 and 62.5 % of patients received adjuvant chemotherapy and radiotherapy, respectively.

Conclusions: Patients with CNS tumours typically had multiple presentations. More extensive surgical resection was associated with higher postoperative morbidities (p = 0.041). The 30-day postoperative morbidity (17.5 %) and mortality (3.5 %) were concordant with the currently available literature.

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