Evaluation of Autonomic Nervous System by Salivary Alpha-amylase Level and Heart Rate Variability in Patients with Schizophrenia

Overview

Journal Eur Arch Psychiatry Clin Neurosci

Specialties Neurology
Psychiatry

Date 2013 May 7

PMID 23645102

Citations 16

Authors

Masa Ieda

Tsuyoshi Miyaoka

Rei Wake

Kristian Liaury

Keiko Tsuchie

Michiyo Fukushima

Tomoko Araki

Satoko Ezoe

Takuji Inagaki

Jun Horiguchi

Affiliations

Soon will be listed here.

Abstract

Several researches indicate that autonomic nervous system (ANS) dysfunction in patients with schizophrenia. Recently, salivary alpha-amylase (sAA) has been employed as a useful marker for ANS function. We investigated the extent of ANS dysfunction by measuring sAA and heart rate variability (HRV) of 25 patients with schizophrenia compared with controls. Schizophrenia group demonstrated a significant increase in sAA and markedly lower parasympathetic nervous system (PNS) activity in the HRV. However, there were no significant differences between two groups in sympathetic nervous system (SNS) activity. We concluded that PNS might be suppressed and the SNS shows relatively high activity in schizophrenia.

Citing Articles

Heart rate variability in schizophrenia: A comparative analysis before and after electroconvulsive therapy.

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Altered Heart Rate Variability During Rest in Schizophrenia: A State Marker.

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