The Responses of the Hepatosomatic Index (HSI), 7-ethoxyresorufin-O-deethylase (EROD) Activity and Glutathione-S-transferase (GST) Activity in Sea Bass (Dicentrarchus Labrax, Linnaeus 1758) Caged at a Polluted Site: Implications for Their Use In...

Overview

Journal Environ Monit Assess

Publisher Springer

Specialty Environmental Health

Date 2013 May 7

PMID 23644668

Citations 2

Authors

Luka Traven

Vladimir Micovic

Darija Vukic Lusic

Tvrtko Smital

Affiliations

Soon will be listed here.

Abstract

The present study investigates the response of three hepatic biomarkers in adult sea bass (Dicentrarchus labrax, Linnaeus 1758) caged at a wastewater outlet of an oil refinery with fish caged at a pristine site used as controls. The biomarkers that were investigated were the hepatosomatic index (HSI), 7-ethoxyresorufin-O-deethylase (EROD) activity and glutathione-S-transferase (GST) activity. In addition, we have measured the levels of polycyclic aromatic hydrocarbons (PAHs) and selected heavy metals (lead, cadmium, mercury, copper and zinc) in sediment samples at the polluted site. Although the polluted site had high environmental levels of PAHs and heavy metals, there was no difference in hepatic EROD activity and HSI between fish caged at the polluted site and controls. On the other hand, GST activity was significantly lower in fish caged at the polluted site compared to controls. Our results point out that the studied biomarkers have limited use in environmental risk assessment studies, at least when caged adult sea bass is used as the sentinel species and complex toxicant mixtures are involved.

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