Chemokines in the Pathogenesis of Endometriosis and Infertility

Overview

Journal J Reprod Immunol

Specialty Allergy & Immunology

Date 2013 Apr 30

PMID 23622730

Citations 24

Authors

G M Borrelli

K I Carvalho

E G Kallas

S Mechsner

E C Baracat

M S Abrao

Affiliations

Soon will be listed here.

Abstract

Endometriosis is a chronic benign disease that affects women of reproductive age causing abdominal pain and infertility. Its pathogenesis remains obscure despite all the research conducted over the past 100 years. However, there is a consensus among the specialists that the basis of its pathophysiology would be multifactorial. Many publications have demonstrated that chemokines are somehow associated with the development of endometriosis and infertility. In this study, we reviewed all PubMed literature using MeSH terms "chemokines" and "endometriosis" as well as "chemokines" and "female infertility" to establish what we know and what we do not yet know about this relationship.

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