» Articles » PMID: 23621964

Posttraumatic Stress Disorder and Cardiovascular Disease

Overview
Date 2013 Apr 30
PMID 23621964
Citations 79
Authors
Affiliations
Soon will be listed here.
Abstract

Posttraumatic stress disorder (PTSD) is an anxiety disorder initiated by exposure to a traumatic event and characterized by intrusive thoughts about the event, attempts to avoid reminders of the event, and physiological hyperarousal. In a number of large prospective observational studies, PTSD has been associated with incident cardiovascular disease (CVD) and mortality. Also, in recent years, a number of studies have shown that cardiovascular events can themselves cause PTSD in more than 1 in 8 patients with acute coronary syndrome. Further, a few small studies suggest that PTSD secondary to an acute CVD event then places patients at increased risk for subsequent CVD events and mortality. In this article, we review the evidence for a link between PTSD and CVD, and discuss potential mechanisms for that association as well as future directions for research.

Citing Articles

A genetic exploration of the relationship between posttraumatic stress disorder and cardiovascular diseases.

Lukas E, Veeneman R, Smit D, Ahluwalia T, Vermeulen J, Pathak G Transl Psychiatry. 2025; 15(1):1.

PMID: 39755697 PMC: 11700205. DOI: 10.1038/s41398-024-03197-z.


Impact of cognitive behavioural therapy on neural, inflammatory, & autonomic markers in a sample with PTSD and cardiovascular risk: protocol for a pilot randomised controlled trial.

Ellis R, Sinnott S, Karam K, Assefa A, Osborne M, Seligowski A Eur J Psychotraumatol. 2024; 15(1):2378618.

PMID: 39045795 PMC: 11271075. DOI: 10.1080/20008066.2024.2378618.


Skin Conductance Reactivity as a Predictor of Stroke-induced Posttraumatic Stress Disorder Symptoms: A Dimensional Approach.

Meinhausen C, Sanchez G, Edmondson D, Kronish I, Schwartz J, Hinrichs R Depress Anxiety. 2024; 2023.

PMID: 39015247 PMC: 11250708. DOI: 10.1155/2023/6671337.


Mediterranean Diet Adherence, Physical Activity, and Advanced Glycation End Products in Complex PTSD: A Comprehensive Examination of Lifestyle and Cardiovascular Risk in War Veterans.

Puljiz Z, Kumric M, Borovina Marasovic T, Mastelic T, Rakusic M, Pavela G Nutrients. 2024; 16(11).

PMID: 38892723 PMC: 11174454. DOI: 10.3390/nu16111791.


Resilience and its influencing factors after emergency percutaneous coronary intervention in young and middle-aged patients with first acute myocardial infarction.

Wang J, Wu Y, Zhou J, Li S, She L Sci Rep. 2024; 14(1):9507.

PMID: 38664486 PMC: 11045793. DOI: 10.1038/s41598-024-59885-9.


References
1.
Wang X, Chung M, Hyland M, Bahkeit M . Posttraumatic stress disorder and psychiatric co-morbidity following stroke: the role of alexithymia. Psychiatry Res. 2010; 188(1):51-7. DOI: 10.1016/j.psychres.2010.10.002. View

2.
Wang P, Berglund P, Olfson M, Pincus H, Wells K, Kessler R . Failure and delay in initial treatment contact after first onset of mental disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005; 62(6):603-13. DOI: 10.1001/archpsyc.62.6.603. View

3.
Dimsdale J . Psychological stress and cardiovascular disease. J Am Coll Cardiol. 2008; 51(13):1237-46. PMC: 2633295. DOI: 10.1016/j.jacc.2007.12.024. View

4.
Freedy J, Steenkamp M, Magruder K, Yeager D, Zoller J, Hueston W . Post-traumatic stress disorder screening test performance in civilian primary care. Fam Pract. 2010; 27(6):615-24. DOI: 10.1093/fampra/cmq049. View

5.
Germain A, Richardson R, Moul D, Mammen O, Haas G, Forman S . Placebo-controlled comparison of prazosin and cognitive-behavioral treatments for sleep disturbances in US Military Veterans. J Psychosom Res. 2012; 72(2):89-96. PMC: 3267960. DOI: 10.1016/j.jpsychores.2011.11.010. View