Microbial Biofilms and Gastrointestinal Diseases

Overview

Journal Pathog Dis

Publisher Oxford University Press

Specialties Infectious Diseases
Microbiology

Date 2013 Apr 27

PMID 23620117

Citations 40

Authors

Erik C von Rosenvinge

Graeme A OMay

Sandra Macfarlane

George T Macfarlane

Mark E Shirtliff

Affiliations

Soon will be listed here.

Abstract

The majority of bacteria live not planktonically, but as residents of sessile biofilm communities. Such populations have been defined as 'matrix-enclosed microbial accretions, which adhere to both biological and nonbiological surfaces'. Bacterial formation of biofilm is implicated in many chronic disease states. Growth in this mode promotes survival by increasing community recalcitrance to clearance by host immune effectors and therapeutic antimicrobials. The human gastrointestinal (GI) tract encompasses a plethora of nutritional and physicochemical environments, many of which are ideal for biofilm formation and survival. However, little is known of the nature, function, and clinical relevance of these communities. This review summarizes current knowledge of the composition and association with health and disease of biofilm communities in the GI tract.

Citing Articles

Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities.

Jandl B, Dighe S, Gasche C, Makristathis A, Muttenthaler M Clin Microbiol Rev. 2024; 37(3):e0013323.

PMID: 38995034 PMC: 11391705. DOI: 10.1128/cmr.00133-23.

Association between gut microbiota and CpG island methylator phenotype in colorectal cancer.

Park P, Keith K, Calendo G, Jelinek J, Madzo J, Gharaibeh R Gut Microbes. 2024; 16(1):2363012.

PMID: 38860458 PMC: 11174071. DOI: 10.1080/19490976.2024.2363012.

Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on the host in a gut microphysiological system.

Hayes J, Lunger A, Sharma A, Fernez M, Carrier R, Koppes A Cell Rep. 2023; 42(12):113481.

PMID: 37980564 PMC: 10791167. DOI: 10.1016/j.celrep.2023.113481.

Biofilm tolerance, resistance and infections increasing threat of public health.

Yang S, Li X, Cang W, Mu D, Ji S, An Y Microb Cell. 2023; 10(11):233-247.

PMID: 37933277 PMC: 10625689. DOI: 10.15698/mic2023.11.807.

Strategy to combat biofilms: a focus on biofilm dispersal enzymes.

Wang S, Zhao Y, Breslawec A, Liang T, Deng Z, Kuperman L NPJ Biofilms Microbiomes. 2023; 9(1):63.

PMID: 37679355 PMC: 10485009. DOI: 10.1038/s41522-023-00427-y.

References

OMay G, Reynolds N, Macfarlane G . Effect of pH on an in vitro model of gastric microbiota in enteral nutrition patients. Appl Environ Microbiol. 2005; 71(8):4777-83. PMC: 1183347. DOI: 10.1128/AEM.71.8.4777-4783.2005. View

Mpofu C, Campbell B, Subramanian S, Marshall-Clarke S, Hart C, Cross A . Microbial mannan inhibits bacterial killing by macrophages: a possible pathogenic mechanism for Crohn's disease. Gastroenterology. 2007; 133(5):1487-98. DOI: 10.1053/j.gastro.2007.08.004. View

STARK R, Gerwig G, Pitman R, Potts L, Williams N, Greenman J . Biofilm formation by Helicobacter pylori. Lett Appl Microbiol. 1999; 28(2):121-6. DOI: 10.1046/j.1365-2672.1999.00481.x. View

Cammarota G, Branca G, Ardito F, Sanguinetti M, Ianiro G, Cianci R . Biofilm demolition and antibiotic treatment to eradicate resistant Helicobacter pylori: a clinical trial. Clin Gastroenterol Hepatol. 2010; 8(9):817-820.e3. DOI: 10.1016/j.cgh.2010.05.006. View

Macfarlane G, Cummings J, Macfarlane S, Gibson G . Influence of retention time on degradation of pancreatic enzymes by human colonic bacteria grown in a 3-stage continuous culture system. J Appl Bacteriol. 1989; 67(5):520-7. View

Mathus-Vliegen E, Bredius M, Binnekade J . Analysis of sites of bacterial contamination in an enteral feeding system. JPEN J Parenter Enteral Nutr. 2006; 30(6):519-25. DOI: 10.1177/0148607106030006519. View

Baumgart M, Dogan B, Rishniw M, Weitzman G, Bosworth B, Yantiss R . Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum. ISME J. 2007; 1(5):403-18. DOI: 10.1038/ismej.2007.52. View

Macfarlane S, Woodmansey E, Macfarlane G . Colonization of mucin by human intestinal bacteria and establishment of biofilm communities in a two-stage continuous culture system. Appl Environ Microbiol. 2005; 71(11):7483-92. PMC: 1287682. DOI: 10.1128/AEM.71.11.7483-7492.2005. View

Croucher S, Houston A, Bayliss C, Turner R . Bacterial populations associated with different regions of the human colon wall. Appl Environ Microbiol. 1983; 45(3):1025-33. PMC: 242405. DOI: 10.1128/aem.45.3.1025-1033.1983. View

10.

Horie H, Kanazawa K, Okada M, Narushima S, Itoh K, Terada A . Effects of intestinal bacteria on the development of colonic neoplasm: an experimental study. Eur J Cancer Prev. 1999; 8(3):237-45. DOI: 10.1097/00008469-199906000-00012. View

11.

Pei Z, Yang L, Peek R, Jr Levine S, Pride D, Blaser M . Bacterial biota in reflux esophagitis and Barrett's esophagus. World J Gastroenterol. 2006; 11(46):7277-83. PMC: 3025696. DOI: 10.3748/wjg.v11.i46.7277. View

12.

Macfarlane S, Dillon J . Microbial biofilms in the human gastrointestinal tract. J Appl Microbiol. 2007; 102(5):1187-96. DOI: 10.1111/j.1365-2672.2007.03287.x. View

13.

Onderdonk A, Bartlett J . Bacteriological studies of experimental ulcerative colitis. Am J Clin Nutr. 1979; 32(1):258-65. DOI: 10.1093/ajcn/32.1.258. View

14.

Horie H, Kanazawa K, Kobayashi E, Okada M, Fujimura A, Yamagiwa S . Effects of intestinal bacteria on the development of colonic neoplasm II. Changes in the immunological environment. Eur J Cancer Prev. 2000; 8(6):533-7. DOI: 10.1097/00008469-199912000-00009. View

15.

Macfarlane S, Furrie E, Macfarlane G, Dillon J . Microbial colonization of the upper gastrointestinal tract in patients with Barrett's esophagus. Clin Infect Dis. 2007; 45(1):29-38. DOI: 10.1086/518578. View

16.

Reiff C, Kelly D . Inflammatory bowel disease, gut bacteria and probiotic therapy. Int J Med Microbiol. 2009; 300(1):25-33. DOI: 10.1016/j.ijmm.2009.08.004. View

17.

Yonezawa H, Osaki T, Kurata S, Zaman C, Hanawa T, Kamiya S . Assessment of in vitro biofilm formation by Helicobacter pylori. J Gastroenterol Hepatol. 2010; 25 Suppl 1:S90-4. DOI: 10.1111/j.1440-1746.2009.06213.x. View

18.

Peek Jr R, Blaser M . Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer. 2002; 2(1):28-37. DOI: 10.1038/nrc703. View

19.

Gisbert J . "Rescue" regimens after Helicobacter pylori treatment failure. World J Gastroenterol. 2008; 14(35):5385-402. PMC: 2744171. DOI: 10.3748/wjg.14.5385. View

20.

Richardson A, Libby S, Fang F . A nitric oxide-inducible lactate dehydrogenase enables Staphylococcus aureus to resist innate immunity. Science. 2008; 319(5870):1672-6. DOI: 10.1126/science.1155207. View