Variety and Complexity of Fluorine-18-labelled Fluoro-2-deoxy-D-glucose Accumulations in the Oral Cavity of Patients with Oral Cancers

Overview

Journal Dentomaxillofac Radiol

Publisher Oxford University Press

Date 2013 Apr 24

PMID 23610089

Citations 5

Authors

S Kito

H Koga

M Kodama

M Habu

S Kokuryo

N Yamamoto

M Oda

T Nishino

M Zhang

K Matsuo

N Wakasugi-Sato

S Matsumoto-Takeda

Y Seta

D Yoshiga

T Kaneuji

S Nogami

I Yoshioka

Y Yamashita

T Tanaka

I Miyamoto

C Kitamura

K Tominaga

Y Morimoto

Affiliations

Soon will be listed here.

Abstract

Objectives: To elucidate the points that require attention when interpreting fluorine-18-labelled fluoro-2-deoxy-d-glucose ((18)F-FDG)/positron emission tomography (PET) images by demonstration of (18)F-FDG accumulation in various areas of the oral cavity other than primary lesions in patients with oral cancers.

Methods: (18)F-FDG accumulations with a maximal standardized uptake value of over 2.5 in various areas of the oral cavity other than primary lesions were identified in 82 patients with oral cancers.

Results: (18)F-FDG/PET-positive areas, excluding primary tumours, included the front intrinsic muscles of the tongue (89.0%), upper and lower marginal parts of the orbicularis oris muscle (64.6%), sublingual glands, palatine tonsil, pharyngeal tonsil, and lingual tonsil. In addition, some areas in the jaws also showed accumulation.

Conclusions: In patients with oral cancers, areas of (18)F-FDG accumulation in the oral cavity should be precisely identified and appropriately diagnosed, because accumulations can be seen in areas other than the primary tumour.

Citing Articles

The relationship between the uptake of alveolar bone inflammation and of cervical lymph nodes on fluoro-2-deoxy-D-glucose positron emission tomography.

Oda M, Koga H, Kataoka S, Yoshii S, Nishina S, Ansai T Dentomaxillofac Radiol. 2024; 53(6):372-381.

PMID: 38781496 PMC: 11358638. DOI: 10.1093/dmfr/twae019.

Maximum standardized uptake value in C-methionine positron emission tomography may predict the prognosis of patients with oral squamous cell carcinoma.

Kuroshima T, Kitagawa Y, Sato J, Watanabe S, Asaka T, Abe T Odontology. 2024; 113(1):372-378.

PMID: 38703257 DOI: 10.1007/s10266-024-00946-w.

Symposium: Imaging modalities for drug-related osteonecrosis of the jaw (5), utility of bone scintigraphy and F-FDG PET/CT in early detection and risk assessment of medication-related osteonecrosis of the jaw (secondary publication).

Watanabe S, Nakajima K, Kinuya S Jpn Dent Sci Rev. 2019; 55(1):76-79.

PMID: 30956739 PMC: 6431786. DOI: 10.1016/j.jdsr.2018.12.002.

Changes in the distributions of fluorine-18-labelled fluoro-2-deoxy-d-glucose accumulation into tongue-related muscles after dissection in patients with tongue cancer.

Kito S, Koga H, Oda M, Tanaka T, Miyamoto I, Kodama M Dentomaxillofac Radiol. 2017; 46(6):20160396.

PMID: 28467114 PMC: 5606277. DOI: 10.1259/dmfr.20160396.

Alterations in 18F-FDG accumulation into neck-related muscles after neck dissection for patients with oral cancers.

Kito S, Koga H, Kodama M, Habu M, Kokuryo S, Oda M Med Oral Patol Oral Cir Bucal. 2016; 21(3):e341-8.

PMID: 27031062 PMC: 4867208. DOI: 10.4317/medoral.21018.

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