Less Invasive Coronary Artery Revascularization with a Minimized Extracorporeal Circulation System: Preliminary Results of a Comparative Study with Off-pump-procedures

Overview

Journal J Cardiothorac Surg

Publisher Biomed Central

Specialties Cardiology & Vascular Diseases
General Surgery
Pulmonary Medicine

Date 2013 Apr 13

PMID 23577663

Citations 3

Authors

Thorsten Wittwer

Anton Sabashnikov

Parwis B Rahmanian

Yeong-Hoon Choi

Mohamed Zeriouh

Thorsten O Mehler

Thorsten Wahlers

Affiliations

Soon will be listed here.

Abstract

Background: Coronary-artery-bypass-grafting (CABG) with conventional extracorporeal circulation (CECC) is associated with adverse effects such as systemic inflammatory response leading to a decrease in systemic vascular resistance and hemodynamic instability. Modern "less invasive" procedures have been established recently which potentially avoid negative side effects of CECC. The aim of this study was to compare perioperative outcome following coronary revascularization using either a minimized extracorporeal circuit (Mini-HLM) or off-pump technique (OPCAB).

Methods: In this prospective ethics-approved trial, 120 patients referred for CABG were randomly assigned either to off-pump coronary artery bypass (OPCAB) or to a Mini-HLM procedure. Patient demographics, preoperative characteristics and extensive postoperative outcome were analyzed for both groups. Hemodynamic data were measured at seven time points perioperatively.

Results: Operation-time was longer in the Mini-HLM group (178,3 ± 32,9 min) compared to OPCAB (133,2 ± 32,7 min, p < 0,001) with higher graft numbers in Mini-HLM group (3,11 ± 0,7 vs. 1,78 ± 0,7, p < 0.001). There were no significant differences in perioperative hemodynamic criteria, catecholaminergic support, hospital (p = 0,534) and intensive care unit stay (p = 0,880), ventilation time (p = 0,113), blood loss (p = 0,570), transfusion requirements, postoperative atrial fibrillation rate (p = 0,706) and neurocognitive disturbance (p = 0,297). No deaths and no myocardial infarctions were observed.

Conclusions: Coronary revascularisation with Mini-HLM represents a suitable and "less invasive" procedure which achieves all benefits of OPCAB but may allow for less demanding revascularisation than OPCAB in special patients with complex coronary anatomy and can therefore be used both on a routine basis and in all "conversion" cases of OPCAB.

Citing Articles

The effect of using the minimized cardio-pulmonary bypass Systems for Coronary Artery Bypass Grafting in diabetic patients.

Albacker T, Fouda M, Bakir B, Eldemerdash A J Cardiothorac Surg. 2021; 16(1):162.

PMID: 34099011 PMC: 8182931. DOI: 10.1186/s13019-021-01551-6.

From less invasive to minimal invasive extracorporeal circulation.

Anastasiadis K, Antonitsis P, Deliopoulos A, Argiriadou H J Thorac Dis. 2021; 13(3):1909-1921.

PMID: 33841979 PMC: 8024827. DOI: 10.21037/jtd-20-1830.

Effects of Minimal Extracorporeal Circulation on the Systemic Inflammatory Response and the Need for Transfusion after Coronary Bypass Grafting Surgery.

Elci M, Kahraman A, Mutlu E, Ispir C Cardiol Res Pract. 2019; 2019:1726150.

PMID: 31275639 PMC: 6589289. DOI: 10.1155/2019/1726150.

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