Novel Pebbles in the Mosaic of Autoimmunity

Overview

Journal BMC Med

Publisher Biomed Central

Specialty General Medicine

Date 2013 Apr 6

PMID 23557479

Citations 11

Authors

Carlo Perricone

Nancy Agmon-Levin

Yehuda Shoenfeld

Affiliations

Soon will be listed here.

Abstract

Almost 25 years ago, the concept of the 'mosaic of autoimmunity' was introduced to the scientific community, and since then this concept has continuously evolved, with new pebbles being added regularly. We are now looking at an era in which the players of autoimmunity have changed names and roles. In this issue of BMC Medicine, several aspects of autoimmunity have been addressed, suggesting that we are now at the forefront of autoimmunity science. Within the environmental factors generating autoimmunity are now included unsuspected molecules such as vitamin D and aluminum. Some adjuvants such as aluminum are recognized as causal factors in the development of the autoimmune response. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), has been recently described. This is the new wind blowing within the branches of autoimmunity, adding knowledge to physicians for helping patients with autoimmune disease.

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