Dermatofibrosarcoma Protuberans (DFSP) Successfully Treated with Sorafenib: Case Report

Overview

Journal Clin Sarcoma Res

Publisher Biomed Central

Date 2013 Apr 6

PMID 23557478

Citations 20

Authors

Francois G Kamar

Victor F Kairouz

Alain N Sabri

Affiliations

Soon will be listed here.

Abstract

DFSP is a locally invasive, slow-growing tumor of the subcutaneous tissue that rarely metastasizes but recurs frequently after surgical excision. We report herein a case of highly recurrent, locally invasive DFSP that failed both postoperative radiation therapy and complete trial of Imatinib, but was successfully treated with Sorafenib, which showed unprecedented response.

Citing Articles

Dermatofibrosarcoma Protuberans in a 12-Year-Old Child: A Rare Case.

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PMID: 39220292 PMC: 11365487. DOI: 10.2147/CCID.S480616.

Low-grade dermatofibrosarcoma protuberance - A rare case report.

Yogesh T, Jha A, Jayaraman S, Jayaraman V J Oral Maxillofac Pathol. 2024; 28(2):315-320.

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Molecular pathways and therapeutic strategies in dermatofibrosarcoma protuberans (DFSP): unravelling the tumor's genetic landscape.

Singh H, Choudhary H, Mandlik D, Magre M, Mohanto S, Ahmed M EXCLI J. 2024; 23:727-762.

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Establishment and characterization of NCC-DFSP5-C1: a novel patient-derived dermatofibrosarcoma protuberans cell line.

Ono T, Noguchi R, Osaki J, Akiyama T, Adachi Y, Kojima N Hum Cell. 2024; 37(3):854-864.

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Multi-omic profiling and real time ex vivo modelling of imatinib-resistant dermatofibrosarcoma protuberans with fibrosarcomatous transformation.

Chan J, Lee E, Li Z, Lee J, Lim A, Poon E Hum Cell. 2023; 36(6):2228-2236.

PMID: 37610680 DOI: 10.1007/s13577-023-00974-8.

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