Liver Transplantation for Recurrent Hepatic Adenoma
Overview
Authors
Affiliations
Hepatic adenoma (HA) is a rare indication for liver transplantation (LTx). So far 20 cases of LTx for HA are reported in PubMed. In rare cases HA presents as multiple hepatic adenomas or recurrent adenoma after initial liver resection and in such cases LTx is the only potential cure and prevents the risk of bleeding or cancer transformation into hepatocellular carcinoma. We report the case of a 56 years old lady who underwent a left hepatectomy for giant adenoma in 2005 and resection of segment V-VI for recurrence of liver adenoma in 2007. She developed a second recurrence of HA with 3 new lesions in the right liver in 2008. The patient underwent LTx. After 3 years the patient is alive with no evidence of disease. LTx is indicated in patients with HA in which resection is not technically feasible.
Indications and outcomes of liver transplantation for liver tumors in the United States.
Okumura K, Dhand A, Hanna K, Misawa R, Sogawa H, Veillette G Surg Pract Sci. 2025; 17():100245.
PMID: 39845637 PMC: 11749412. DOI: 10.1016/j.sipas.2024.100245.
Rocha P, Leal N, Barbosa M, De Resende J, Rodrigues P Cureus. 2022; 14(8):e27788.
PMID: 36106301 PMC: 9449253. DOI: 10.7759/cureus.27788.
A Scoping Review of the Classification, Diagnosis, and Management of Hepatic Adenomas.
Aziz H, Brown Z, Eskander M, Aquina C, Baghdadi A, Kamel I J Gastrointest Surg. 2022; 26(4):965-978.
PMID: 35083725 DOI: 10.1007/s11605-022-05246-8.
Ziogas I, Tasoudis P, Serifis N, Alexopoulos S, Montenovo M, Shingina A Transplant Direct. 2022; 8(2):e1264.
PMID: 35018302 PMC: 8735769. DOI: 10.1097/TXD.0000000000001264.
Clinicopathological features and post-resection outcomes of hepatocellular adenoma.
Kim S, Hwang S, Ahn C, Kim K, Moon D, Ha T Ann Hepatobiliary Pancreat Surg. 2021; 25(1):25-33.
PMID: 33649251 PMC: 7952660. DOI: 10.14701/ahbps.2021.25.1.25.