125I Seed Implant Brachytherapy for the Treatment of Parotid Gland Cancers in Children and Adolescents

Overview

Journal Strahlenther Onkol

Specialties Oncology
Radiology

Date 2013 Mar 23

PMID 23519359

Citations 7

Authors

L Zheng

T Song

J Zhang

G Yu

Y Zhang

Affiliations

Soon will be listed here.

Abstract

Background And Purpose: There is a lack of optimal treatment strategies for managing salivary gland cancers in children and adolescents. This study is aimed at assessing the effect of (125)I seed implantation for the treatment of parotid cancers in children and adolescents.

Patients And Methods: A total of 12 patients younger than 16 years with parotid gland malignant tumors underwent (125)I seed implant brachytherapy between October 2003 and November 2008. All patients were assessed after treatment and at the local tumor control appointments. Facial nerve function, maxillofacial development, and radioactive side-effects were assessed.

Results: The follow-up period ranged from 41-104 months. One patient with T4b died of pulmonary metastasis. The other patients were alive during the follow-up period. There were no serious radiation-related complications. The treatment did not affect facial nerve function and dentofacial growth in any of the children.

Conclusion: For parotid gland cancers in children, (125)I seed implant brachytherapy may be an acceptable treatment without serious complications and with satisfactory short-term effects.

Citing Articles

[Study of surgery combined with I brachytherapy for adenoid cystic carcinoma of oral and maxillofacial region].

Li C, Liu S, Zheng L, Huang M, Shi Y, Lv X Beijing Da Xue Xue Bao Yi Xue Ban. 2019; 51(1):49-52.

PMID: 30773543 PMC: 7433547. DOI: 10.19723/j.issn.1671-167X.2019.01.009.

I brachytherapy of locally advanced non-small-cell lung cancer after one cycle of first-line chemotherapy: a comparison with best supportive care.

Song J, Fan X, Zhao Z, Chen M, Chen W, Wu F Onco Targets Ther. 2017; 10:1345-1352.

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The efficacy of iodine-125 permanent brachytherapy versus intensity-modulated radiation for inoperable salivary gland malignancies: study protocol of a randomised controlled trial.

Liu S, Wang H, Sun Y, Shi Y, Zhang J, Huang M BMC Cancer. 2016; 16:193.

PMID: 26951097 PMC: 4782516. DOI: 10.1186/s12885-016-2248-7.

Three-dimensional verification of ¹²⁵I seed stability after permanent implantation in the parotid gland and periparotid region.

Fan Y, Huang M, Zheng L, Zhao Y, Zhang J Radiat Oncol. 2015; 10:242.

PMID: 26597296 PMC: 4657216. DOI: 10.1186/s13014-015-0552-z.

125I Seed Implant Brachytherapy for Painful Bone Metastases After Failure of External Beam Radiation Therapy.

Feng S, Wang L, Xiao Z, Maharjan R, Chuanxing L, Fujun Z Medicine (Baltimore). 2015; 94(31):e1253.

PMID: 26252288 PMC: 4616588. DOI: 10.1097/MD.0000000000001253.

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