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Varicella Zoster Virus Infection Presenting As Isolated Diplopia: a Case Report

Overview
Journal BMC Infect Dis
Publisher Biomed Central
Specialty Infectious Diseases
Date 2013 Mar 19
PMID 23497310
Citations 4
Authors
Raffaella Pisapia
Alessia Rianda
Andrea Mariano
Angela Testa
Simonetta Galgani
Laura Vincenzi
Amina Abdeddaim
Alessandra Oliva
Pasquale Narciso
Affiliations
Soon will be listed here.
Abstract

Background: Involvement of trochlear nerve during Varicella Zoster Virus (VZV) Infection has been rarely described, and always in association with skin rash.

Case Presentation: We describe the case of a patient with VZV infection presenting as isolated diplopia due to fourth cranial nerve palsy. The diagnosis has been obtained through the application of a standardized molecular diagnostic panel, and diplopia resolved after specific antiviral and corticosteroid therapy.

Conclusion: This case evidences that clinicians should be aware of atypical VZV infection, even in the absence of the typical skin rash.

Citing Articles

Cranial nerve involvement in varicella zoster virus after renal transplantation.

Nielsen Fan J, Fan J, Ali H Proc (Bayl Univ Med Cent). 2020; 33(4):612-613.

PMID: 33100543 PMC: 7549937. DOI: 10.1080/08998280.2020.1775031.

Diplopia as isolated presentation of varicella zoster central nervous system reactivation.

Borgo C, Belvisi V, Valli M, Curra A, Pozzetto I, Sepe M J Neurovirol. 2017; 23(4):621-624.

PMID: 28560630 DOI: 10.1007/s13365-017-0534-z.

Varicella vasculopathy and chronic suppurative otitis media: Differential diagnosis for isolated sixth nerve palsy.

Venugopal N Indian J Ophthalmol. 2015; 63(10):806.

PMID: 26655013 PMC: 4728988. DOI: 10.4103/0301-4738.171531.

Commentary.

McDonald E, Patel D J Neurosci Rural Pract. 2014; 5(2):182-3.

PMID: 24966564 PMC: 4064191. DOI: 10.4103/0976-3147.131674.

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