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A Decision Analysis Tool for the Assessment of Posterior Fossa Tumour Surgery Outcomes in Children--the "Liverpool Neurosurgical Complication Causality Assessment Tool"

Overview
Specialty Pediatrics
Date 2013 Mar 16
PMID 23494657
Citations 1
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Abstract

Introduction: Complications may occur following posterior fossa tumour surgery in children. Such complications are subjectively and inconsistently reported even though they may have significant long-term behavioural and cognitive consequences for the child. This makes comparison of surgeons, programmes and treatments problematic.

Materials And Methods: We have devised a causality tool for assessing if an adverse event after surgery can be classified as a surgical complication using a series of simple questions, based on a tool used in assessing adverse drug reactions. This tool, which we have called the "Liverpool Neurosurgical Complication Causality Assessment Tool", was developed by reviewing a series of ten posterior fossa tumour cases with a panel of neurosurgery, neurology, oncology and neuropsychology specialists working in a multidisciplinary paediatric tumour treatment programme.

Discussion And Conclusion: We have demonstrated its use and hope that it may improve reliability between different assessors both in evaluating the outcomes of existing programmes and treatments as well as aiding in trials which may directly compare the effects of surgical and medical treatments.

Citing Articles

Pediatric medulloblastoma - update on molecular classification driving targeted therapies.

deSouza R, Jones B, Lowis S, Kurian K Front Oncol. 2014; 4:176.

PMID: 25101241 PMC: 4105823. DOI: 10.3389/fonc.2014.00176.

References
1.
Shanmugam G, Clark L, Burton H, Warren A, OBlenes S, Hancock Friesen C . Improving and standardizing capture of pediatric cardiac surgical complications. J Thorac Cardiovasc Surg. 2012; 144(3):570-6. DOI: 10.1016/j.jtcvs.2012.01.070. View

2.
Ozgur B, Berberian J, Aryan H, Meltzer H, Levy M . The pathophysiologic mechanism of cerebellar mutism. Surg Neurol. 2006; 66(1):18-25. DOI: 10.1016/j.surneu.2005.12.003. View

3.
Di Rocco C, Chieffo D, Pettorini B, Massimi L, Caldarelli M, Tamburrini G . Preoperative and postoperative neurological, neuropsychological and behavioral impairment in children with posterior cranial fossa astrocytomas and medulloblastomas: the role of the tumor and the impact of the surgical treatment. Childs Nerv Syst. 2010; 26(9):1173-88. DOI: 10.1007/s00381-010-1166-2. View

4.
Orgel E, Jain S, Ji L, Pollick L, Si S, Finlay J . Hearing loss among survivors of childhood brain tumors treated with an irradiation-sparing approach. Pediatr Blood Cancer. 2011; 58(6):953-8. DOI: 10.1002/pbc.23275. View

5.
Dubey A, Sung W, Shaya M, Patwardhan R, Willis B, Smith D . Complications of posterior cranial fossa surgery--an institutional experience of 500 patients. Surg Neurol. 2009; 72(4):369-75. DOI: 10.1016/j.surneu.2009.04.001. View