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EDAM: an Ontology of Bioinformatics Operations, Types of Data and Identifiers, Topics and Formats

Overview
Journal Bioinformatics
Specialty Biology
Date 2013 Mar 13
PMID 23479348
Citations 105
Authors
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Abstract

Motivation: Advancing the search, publication and integration of bioinformatics tools and resources demands consistent machine-understandable descriptions. A comprehensive ontology allowing such descriptions is therefore required.

Results: EDAM is an ontology of bioinformatics operations (tool or workflow functions), types of data and identifiers, application domains and data formats. EDAM supports semantic annotation of diverse entities such as Web services, databases, programmatic libraries, standalone tools, interactive applications, data schemas, datasets and publications within bioinformatics. EDAM applies to organizing and finding suitable tools and data and to automating their integration into complex applications or workflows. It includes over 2200 defined concepts and has successfully been used for annotations and implementations.

Availability: The latest stable version of EDAM is available in OWL format from http://edamontology.org/EDAM.owl and in OBO format from http://edamontology.org/EDAM.obo. It can be viewed online at the NCBO BioPortal and the EBI Ontology Lookup Service. For documentation and license please refer to http://edamontology.org. This article describes version 1.2 available at http://edamontology.org/EDAM_1.2.owl.

Contact: jison@ebi.ac.uk.

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References
1.
Ashburner M, Mungall C, Lewis S . Ontologies for biologists: a community model for the annotation of genomic data. Cold Spring Harb Symp Quant Biol. 2004; 68:227-35. DOI: 10.1101/sqb.2003.68.227. View

2.
Lamprecht A, Naujokat S, Margaria T, Steffen B . Semantics-based composition of EMBOSS services. J Biomed Semantics. 2011; 2 Suppl 1:S5. PMC: 3105497. DOI: 10.1186/2041-1480-2-S1-S5. View

3.
Eilbeck K, Lewis S, Mungall C, Yandell M, Stein L, Durbin R . The Sequence Ontology: a tool for the unification of genome annotations. Genome Biol. 2005; 6(5):R44. PMC: 1175956. DOI: 10.1186/gb-2005-6-5-r44. View

4.
Ashburner M, Ball C, Blake J, Botstein D, Butler H, Cherry J . Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000; 25(1):25-9. PMC: 3037419. DOI: 10.1038/75556. View

5.
Grenon P, Smith B, Goldberg L . Biodynamic ontology: applying BFO in the biomedical domain. Stud Health Technol Inform. 2005; 102:20-38. View