Reliability and Validity of a MR-based Volumetric Analysis of the Intrinsic Foot Muscles

Overview

Journal J Magn Reson Imaging

Date 2013 Mar 2

PMID 23450691

Citations 16

Authors

Victor A Cheuy

Paul K Commean

Mary K Hastings

Michael J Mueller

Affiliations

Soon will be listed here.

Abstract

Purpose: To describe a semi-automated program that will segment subcutaneous fat, muscle, and adipose tissue in the foot using MR imaging, determine the reliability of the program between and within raters, and determine the validity of the program using MR phantoms.

Materials And Methods: MR images were acquired from 19 subjects with and without diabetes and peripheral neuropathy. Two raters segmented and measured volumes from single MR slices at the forefoot, midfoot, and hindfoot at two different times. Intra- and inter-rater correlation coefficients were determined. Muscle and fat MR phantoms of known volumes were measured by the program.

Results: Most ICC reliability values were over 0.950. Validity estimates comparing MR estimates and known volumes resulted in r(2) values above 0.970 for all phantoms. The root mean square error was less than 5% for all phantoms.

Conclusion: Subcutaneous fat, lean muscle, and adipose tissue volumes in the foot can be quantified in a reliable and valid way. This program can be applied in future studies investigating the relationship of these foot structures to functions in important pathologies, including the neuropathic foot or other musculoskeletal problems.

Citing Articles

Sarcopenia in the foot on magnetic resonance imaging in patients with diabetes mellitus - a systematic review.

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Use of computed tomography to identify muscle quality subgroups, spatial mapping, and preliminary relationships to function in those with diabetic peripheral neuropathy.

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Computed Tomography and Magnetic Resonance Correlation and Agreement for Foot Muscle and Adipose Tissue Measurements.

Commean P, Mueller M, Chen L, Wolfsberger M, Hastings M J Comput Assist Tomogr. 2022; 46(2):212-218.

PMID: 35297577 PMC: 9231651. DOI: 10.1097/RCT.0000000000001275.

Body mass index and maximum available midfoot motion are associated with midfoot angle at peak heel rise in people with type 2 diabetes mellitus and peripheral neuropathy.

Jeong H, Mueller M, Zellers J, Commean P, Chen L, Hastings M Foot (Edinb). 2022; 51:101912.

PMID: 35255403 PMC: 9169461. DOI: 10.1016/j.foot.2022.101912.

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