Alpha 2.0
Login Register
» Articles » PMID: 23444037

A New Nematicidal Compound Produced by Streptomyces Albogriseolus HA10002

Overview
Journal Antonie Van Leeuwenhoek
Publisher Springer
Specialty Microbiology
Date 2013 Feb 28
PMID 23444037
Citations 13
Authors
Qingfei Zeng
Huiqin Huang
Jun Zhu
Zhe Fang
Qianguang Sun
Shixiang Bao
Affiliations
Soon will be listed here.
Abstract

Strain HA10002 was isolated from mangrove sediment collected from Dongzhaigang Mangrove Reserve in Hainan, China. It was selected with potent nematicidal activity and was identified as Streptomyces albogriseolus. By bioassay-guided fractionation, a new active component A22-1(S1) against root-knot nematodes was separated from its fermentation broth. On the basis of spectroscopic analyses and comparison with the data from correlative literature, the structure of S1 was established to be 6'-methyl-fungichromin, named as fungichromin B in this paper. The LD50 values of fungichromin B to the 2-stage juveniles of Meloidogyne incognita and Meloidogyne javanica were 7.64 and 7.83 μg/ml, respectively. Further examination demonstrated fungichromin B still showed a wide antifungal spectrum, as with fungichromin.

Citing Articles

Antifungal Natural Products Originating from Endophytic and Rhizospheric Microbes Isolated from Coastal Vegetation.

Jayaweera S, Van T, Dias D J Xenobiot. 2025; 15(1).

PMID: 39997375 PMC: 11856389. DOI: 10.3390/jox15010032.

Potential of different species of actinobacteria in the management of Meloidogyne javanica.

Mogollon-Ortiz A, Monteiro T, de Freitas L, de Queiroz M Arch Microbiol. 2024; 206(4):160.

PMID: 38483595 DOI: 10.1007/s00203-024-03874-z.

Biological Control of Severe Fungal Phytopathogens by Strain CARA17 and Its Bioactive Crude Extracts on Lettuce Plants.

Carlucci A, Sorbo A, Colucci D, Raimondo M Plants (Basel). 2023; 12(10).

PMID: 37653942 PMC: 10220785. DOI: 10.3390/plants12102025.

Insights into the phylogenetic diversity, biological activities, and biosynthetic potential of mangrove rhizosphere Actinobacteria from Hainan Island.

Ye J, Zou R, Zhou D, Deng X, Wu N, Chen D Front Microbiol. 2023; 14:1157601.

PMID: 37323895 PMC: 10264631. DOI: 10.3389/fmicb.2023.1157601.

Stress-Resistance and Growth-Promoting Characteristics and Effects on Vegetable Seed Germination of Streptomyces sp. Strains Isolated from Wetland Plant Rhizospheres.

Zhang H, Bai X, Han Y, Han L Curr Microbiol. 2023; 80(5):190.

PMID: 37079055 DOI: 10.1007/s00284-023-03297-x.

References
1.
Trudgill D, Blok V . Apomictic, polyphagous root-knot nematodes: exceptionally successful and damaging biotrophic root pathogens. Annu Rev Phytopathol. 2001; 39:53-77. DOI: 10.1146/annurev.phyto.39.1.53. View
2.
Ayers S, Zink D, Mohn K, Powell J, Brown C, Murphy T . Anthelmintic macrolactams from Nonomuraea turkmeniaca MA7364. J Nat Prod. 2007; 70(8):1371-3. DOI: 10.1021/np070131e. View
3.
Wang X, Wang M, Wang J, Jiang L, Wang J, Xiang W . Isolation and identification of novel macrocyclic lactones from Streptomyces avermitilis NEAU1069 with acaricidal and nematocidal activity. J Agric Food Chem. 2009; 58(5):2710-4. DOI: 10.1021/jf902496d. View
4.
BeBoer C, Dietz A . The description and antibiotic production of Streptomyces hygroscopicus var. Geldanus. J Antibiot (Tokyo). 1976; 29(11):1182-8. DOI: 10.7164/antibiotics.29.1182. View
5.
Capon R, Skene C, Lacey E, Gill J, Wicker J, Heiland K . Lorneamides A and B: two new aromatic amides from a southern Australian marine actinomycete. J Nat Prod. 2001; 63(12):1682-3. DOI: 10.1021/np000241k. View