Unbalanced Neuronal Circuits in Addiction

Overview

Journal Curr Opin Neurobiol

Specialties Biology
Neurology

Date 2013 Feb 26

PMID 23434063

Citations 96

Authors

Nora D Volkow

Gen-Jack Wang

Dardo Tomasi

Ruben D Baler

Affiliations

Soon will be listed here.

Abstract

Through sequential waves of drug-induced neurochemical stimulation, addiction co-opts the brain's neuronal circuits that mediate reward, motivation to behavioral inflexibility and a severe disruption of self-control and compulsive drug intake. Brain imaging technologies have allowed neuroscientists to map out the neural landscape of addiction in the human brain and to understand how drugs modify it.

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