Double-ligand Modulation for Engineering Magnetic Nanoclusters

Overview

Journal Nanoscale Res Lett

Publisher Springer

Specialty Biotechnology

Date 2013 Feb 26

PMID 23433032

Citations 2

Authors

Bongjune Kim

Jaemoon Yang

Eun-Kyung Lim

Joseph Park

Jin-Suck Suh

Hyo Seon Park

Yong-Min Huh

Seungjoo Haam

Affiliations

Soon will be listed here.

Abstract

Magnetic nanoclusters (MNCs) are agglomerated individual magnetic nanoparticles (MNPs) that show great promise in increasing magnetic resonance imaging (MRI) sensitivity. Here, we report an effective strategy to engineer MNCs based on double-ligand modulation to enhance MRI sensitivity. The oleic acid-coated individual MNPs self-assembled and then were enveloped by polysorbate 80, using a nanoemulsion method to prepare MNCs. By modulating the amounts of the two ligands, and thus the size and magnetic content of the resultant MNCs, we were able to enormously improve MRI sensitivity.

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