Isothermal Amplification System Based on Template-dependent Extension
Overview
Affiliations
A novel template-dependent extension based isothermal amplification (TEIA) system with high single-base discrimination capability is developed, where the interference caused by non-specific reaction in isothermal strand displacement amplification (SDA) technique is substantially avoided via using a functionalized template probe, showing potential value in the development and application of SDA based detection devices.
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PMID: 35563012 PMC: 9100243. DOI: 10.3390/ijms23094620.
A Biofunctional Molecular Beacon for Detecting Single Base Mutations in Cancer Cells.
Dong H, Ma J, Wang J, Wu Z, Sinko P, Jia L Mol Ther Nucleic Acids. 2016; 5:e302.
PMID: 27045206 PMC: 5014519. DOI: 10.1038/mtna.2016.18.