» Articles » PMID: 23384146

The Unsolved "solved-problem" of Protein Folding

Overview
Date 2013 Feb 7
PMID 23384146
Citations 3
Authors
Affiliations
Soon will be listed here.
Citing Articles

Commonly used FRET fluorophores promote collapse of an otherwise disordered protein.

Riback J, Bowman M, Zmyslowski A, Plaxco K, Clark P, Sosnick T Proc Natl Acad Sci U S A. 2019; 116(18):8889-8894.

PMID: 30992378 PMC: 6500129. DOI: 10.1073/pnas.1813038116.


Potential Inherent Stimulation of the Innate Immune System by Nucleic Acid Aptamers and Possible Corrective Approaches.

Bruno J Pharmaceuticals (Basel). 2018; 11(3).

PMID: 29937498 PMC: 6161019. DOI: 10.3390/ph11030062.


REMD and umbrella sampling simulations to probe the energy barrier of the folding pathways of engrailed homeodomain.

Jani V, Sonavane U, Joshi R J Mol Model. 2014; 20(6):2283.

PMID: 24863533 DOI: 10.1007/s00894-014-2283-8.

References
1.
Myslinski J, Delorbe J, Clements J, Martin S . Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J Am Chem Soc. 2011; 133(46):18518-21. PMC: 3218293. DOI: 10.1021/ja2068752. View

2.
Auton M, Rosgen J, Sinev M, Holthauzen L, Bolen D . Osmolyte effects on protein stability and solubility: a balancing act between backbone and side-chains. Biophys Chem. 2011; 159(1):90-9. PMC: 3166983. DOI: 10.1016/j.bpc.2011.05.012. View

3.
Street T, Bolen D, Rose G . A molecular mechanism for osmolyte-induced protein stability. Proc Natl Acad Sci U S A. 2006; 103(38):13997-4002. PMC: 1564065. DOI: 10.1073/pnas.0606236103. View

4.
Auton M, Bolen D . Predicting the energetics of osmolyte-induced protein folding/unfolding. Proc Natl Acad Sci U S A. 2005; 102(42):15065-8. PMC: 1257718. DOI: 10.1073/pnas.0507053102. View

5.
Cheng Y, Rossky P . Surface topography dependence of biomolecular hydrophobic hydration. Nature. 1998; 392(6677):696-9. DOI: 10.1038/33653. View