Systolic Blood Pressure Reactivity During Submaximal Exercise and Acute Psychological Stress in Youth

Overview

Journal Am J Hypertens

Publisher Oxford University Press

Specialty Cardiology & Vascular Diseases

Date 2013 Feb 6

PMID 23382492

Citations 4

Authors

Maya J Lambiase

Joan Dorn

James N Roemmich

Affiliations

Soon will be listed here.

Abstract

Background: Studies in youth show an association between systolic blood pressure (SBP) reactivity to acute psychological stress and carotid artery intima-media thickness (CIMT). Submaximal exercise produces similar cardiovascular responses as acute psychological stress and may be a valuable tool to assess SBP reactivity in youth. However, it has not yet been determined whether SBP reactivity during submaximal exercise in youth is associated with CIMT, as it is during psychological stress.

Methods: Fifty-four adolescents aged 13-16 years completed 3 visits. On one visit, adolescents completed three, 4-minute stages of increasing intensity on a treadmill. On another visit, adolescents completed measures of acute psychological stress reactivity (star tracing, speech preparation, speech). On a third visit, adolescents completed an ultrasound scan to measure CIMT.

Results: SBP reactivity during lower- (β = 0.29, P = 0.03) and higher-intensity (β = 0.31, P = 0.02) submaximal exercise was associated with greater CIMT. SBP reactivity during higher-intensity submaximal exercise was positively associated with SBP reactivity during star tracing (β = 0.34, P = 0.01), speech preparation (β = 0.37, P = 0.007), and speech (β = 0.41, P = 0.003).

Conclusions: Greater SBP reactivity during submaximal exercise in healthy adolescents was associated with greater CIMT, similar to SBP reactivity during acute psychological stress. Adolescents who had greater SBP reactivity during exercise also demonstrated greater SBP reactivity during the psychological stress tasks. Given that exercise testing can be standardized for comparison across studies, submaximal exercise tests may be a valuable tool to assess SBP reactivity in youth.

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References

Thomas R, Liu K, Jacobs Jr D, Bild D, Kiefe C, Hulley S . Positional change in blood pressure and 8-year risk of hypertension: the CARDIA Study. Mayo Clin Proc. 2003; 78(8):951-8. DOI: 10.4065/78.8.951. View

Roemmich J, Lobarinas C, Joseph P, Lambiase M, Archer Iii F, Dorn J . Cardiovascular reactivity to psychological stress and carotid intima-media thickness in children. Psychophysiology. 2009; 46(2):293-9. DOI: 10.1111/j.1469-8986.2008.00776.x. View

Urbina E, Williams R, Alpert B, Collins R, Daniels S, Hayman L . Noninvasive assessment of subclinical atherosclerosis in children and adolescents: recommendations for standard assessment for clinical research: a scientific statement from the American Heart Association. Hypertension. 2009; 54(5):919-50. DOI: 10.1161/HYPERTENSIONAHA.109.192639. View

Lambiase M, Dorn J, Roemmich J . Metabolic and cardiovascular adjustments during psychological stress and carotid artery intima-media thickness in youth. Physiol Behav. 2012; 105(5):1140-7. DOI: 10.1016/j.physbeh.2011.12.012. View

Taras H, Sallis J . Blood pressure reactivity in young children: comparing three stressors. J Dev Behav Pediatr. 1992; 13(1):41-5. View

Verhaaren H, Schieken R, Schwartz P, Mosteller M, Matthys D, Maes H . Cardiovascular reactivity in isometric exercise and mental arithmetic in children. J Appl Physiol (1985). 1994; 76(1):146-50. DOI: 10.1152/jappl.1994.76.1.146. View

Raitakari O, Juonala M, Kahonen M, Taittonen L, Laitinen T, Maki-Torkko N . Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. JAMA. 2003; 290(17):2277-83. DOI: 10.1001/jama.290.17.2277. View

Low C, Salomon K, Matthews K . Chronic life stress, cardiovascular reactivity, and subclinical cardiovascular disease in adolescents. Psychosom Med. 2009; 71(9):927-31. PMC: 2783997. DOI: 10.1097/PSY.0b013e3181ba18ed. View

Vale S . Psychosocial stress and cardiovascular diseases. Postgrad Med J. 2005; 81(957):429-35. PMC: 1743305. DOI: 10.1136/pgmj.2004.028977. View

10.

Musante L, Raunikar R, Treiber F, Davis H, Dysart J, Levy M . Consistency of children's hemodynamic responses to laboratory stressors. Int J Psychophysiol. 1994; 17(1):65-71. DOI: 10.1016/0167-8760(94)90056-6. View

11.

Lynch J, Kaplan G, Salonen R, Cohen R, Salonen J . Socioeconomic status and carotid atherosclerosis. Circulation. 1995; 92(7):1786-92. DOI: 10.1161/01.cir.92.7.1786. View

12.

Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N . Heart disease and stroke statistics--2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2007; 117(4):e25-146. DOI: 10.1161/CIRCULATIONAHA.107.187998. View

13.

Cuomo S, Guarini P, Gaeta G, De Michele M, BOERI F, Dorn J . Increased carotid intima-media thickness in children-adolescents, and young adults with a parental history of premature myocardial infarction. Eur Heart J. 2002; 23(17):1345-50. DOI: 10.1053/euhj.2001.3111. View

14.

Matthews K, Rakaczky C, Stoney C, Manuck S . Are cardiovascular responses to behavioral stressors a stable individual difference variable in childhood?. Psychophysiology. 1987; 24(4):464-73. DOI: 10.1111/j.1469-8986.1987.tb00318.x. View

15.

Beauloye V, Zech F, Tran H, Clapuyt P, Maes M, Brichard S . Determinants of early atherosclerosis in obese children and adolescents. J Clin Endocrinol Metab. 2007; 92(8):3025-32. DOI: 10.1210/jc.2007-0619. View

16.

Matthews K, Woodall K, Stoney C . Changes in and stability of cardiovascular responses to behavioral stress: results from a four-year longitudinal study of children. Child Dev. 1990; 61(4):1134-44. View

17.

T-M W, Lu L, Ye X, Li S, Wang L . Impact of postures on blood pressure in healthy subjects. Acta Clin Belg. 2009; 63(6):376-80. DOI: 10.1179/acb.2008.078. View

18.

Li S, Chen W, Srinivasan S, Bond M, Tang R, Urbina E . Childhood cardiovascular risk factors and carotid vascular changes in adulthood: the Bogalusa Heart Study. JAMA. 2003; 290(17):2271-6. DOI: 10.1001/jama.290.17.2271. View

19.

Nettlefold L, McKay H, Naylor P, Bredin S, Warburton D . The relationship between objectively measured physical activity, sedentary time, and vascular health in children. Am J Hypertens. 2012; 25(8):914-9. DOI: 10.1038/ajh.2012.68. View

20.

Shapiro D, Jamner L, Lane J, Light K, Myrtek M, Sawada Y . Blood pressure publication guidelines. Society for Psychophysical Research. Psychophysiology. 1996; 33(1):1-12. DOI: 10.1111/j.1469-8986.1996.tb02103.x. View