Role of Skin Prick Test in Allergic Disorders: a Prospective Study in Kashmiri Population in Light of Review

Overview

Journal Indian J Dermatol

Specialty Dermatology

Date 2013 Feb 2

PMID 23372205

Citations 11

Authors

Roohi Rasool

Irfan Ali Shera

Saniya Nissar

Zaffar A Shah

Niyaz Nayak

Mushtaq A Siddiqi

Aga Syed Sameer

Affiliations

Soon will be listed here.

Abstract

Background: Skin prick test (SPT) is the most effective diagnostic test to detect IgE mediated type I allergic reactions like allergic rhinitis, atopic asthma, acute urticaria, food allergy etc. SPTs are done to know allergic sensitivity and applied for devising immunotherapy as the therapeutic modality.

Materials And Methods: This prospective study was conducted in the department of Immunology and Molecular medicine at SKIMS. A total of 400 patients suffering from allergic rhinitis, asthma and urticaria were recruited in this study. SPT was performed with panel of allergens including house dust mite, pollens, fungi, dusts, cockroach, sheep wool and dog epithelia. Allergen immunotherapy was given to allergic rhinitis and asthmatic patients as therapeutic modality.

Results: In our study, age of patients ranged from 6 to 65 years. Majority of patients were in the age group of 20-30 years (72%) with Male to female ratio of 1:1.5. Of the 400 patients, 248 (62%) had urticaria, 108 (27%) patients had allergic rhinitis and 44 (11%) patients had asthma. SPT reaction was positive in 38 (86.4%) with allergic asthma, 74 (68.5%) patients with allergic rhinitis and 4 (1.6%) patient with urticaria, respectively. Allergen immunotherapy was effective in 58% patients with allergic rhinitis and 42% allergic asthma.

Conclusion: Identifiable aeroallergen could be detected in 86.4% allergic asthma and 68.5% allergic rhinitis patients by SPT alone. Pollens were the most prevalent causative allergen. There was significant relief in the severity of symptoms, medication intake with the help of allergen immunotherapy.

Citing Articles

Skin Prick Tests and Enzyme-Linked Immunosorbent Assays among Allergic Patients Using Allergenic Local Pollen Extracts.

Castor M, Cruz M, Hate K, Balanag G, Reyes R, Agcaoili-De Jesus M Acta Med Philipp. 2024; 58(16):23-29.

PMID: 39399369 PMC: 11467584. DOI: 10.47895/amp.v58i16.7741.

Unveiling a Rare Phenomenon: Sudden Sensorineural Hearing Loss Following Skin Prick Testing.

Kataria A, Kangan Indian J Otolaryngol Head Neck Surg. 2024; 76(5):4709-4712.

PMID: 39376315 PMC: 11456135. DOI: 10.1007/s12070-024-04789-3.

Dominant Aero-Allergens Involved in Causing Allergic Rhinitis with Special Reference to Dust Mite Allergy and Skin Prick Test in Tripura: A Prospective Study.

Deb T Indian J Otolaryngol Head Neck Surg. 2022; 74(Suppl 2):1028-1032.

PMID: 36452553 PMC: 9701971. DOI: 10.1007/s12070-020-02108-0.

Study of Allergen Patterns in Cases of Moderate to Severe Persistent Allergic Rhinitis in Central India.

Jain S, Jain A, Gupta S Indian J Otolaryngol Head Neck Surg. 2022; 74(Suppl 2):888-893.

PMID: 36452541 PMC: 9702131. DOI: 10.1007/s12070-020-01954-2.

Trends of sensitization pattern to aeroallergens among the patients with allergic rhinitis and/or bronchial asthma in Bangalore: A cross sectional study.

Shikha G, Swami H Med J Armed Forces India. 2022; 78(4):430-436.

PMID: 36267519 PMC: 9577270. DOI: 10.1016/j.mjafi.2020.11.017.

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