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Nutrient Timing Revisited: is There a Post-exercise Anabolic Window?

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Date 2013 Jan 31
PMID 23360586
Citations 35
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Abstract

Nutrient timing is a popular nutritional strategy that involves the consumption of combinations of nutrients--primarily protein and carbohydrate--in and around an exercise session. Some have claimed that this approach can produce dramatic improvements in body composition. It has even been postulated that the timing of nutritional consumption may be more important than the absolute daily intake of nutrients. The post-exercise period is widely considered the most critical part of nutrient timing. Theoretically, consuming the proper ratio of nutrients during this time not only initiates the rebuilding of damaged muscle tissue and restoration of energy reserves, but it Does So in a supercompensated fashion that enhances both body composition and exercise performance. Several researchers have made reference to an anabolic "window of opportunity" whereby a limited time exists after training to optimize training-related muscular adaptations. However, the importance - and even the existence - of a post-exercise 'window' can vary according to a number of factors. Not only is nutrient timing research open to question in terms of applicability, but recent evidence has directly challenged the classical view of the relevance of post-exercise nutritional intake with respect to anabolism. Therefore, the purpose of this paper will be twofold: 1) to review the existing literature on the effects of nutrient timing with respect to post-exercise muscular adaptations, and; 2) to draw relevant conclusions that allow practical, evidence-based nutritional recommendations to be made for maximizing the anabolic response to exercise.

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References
1.
Cribb P, Hayes A . Effects of supplement timing and resistance exercise on skeletal muscle hypertrophy. Med Sci Sports Exerc. 2006; 38(11):1918-25. DOI: 10.1249/01.mss.0000233790.08788.3e. View

2.
Tarnopolsky M, Bosman M, Macdonald J, Vandeputte D, Martin J, Roy B . Postexercise protein-carbohydrate and carbohydrate supplements increase muscle glycogen in men and women. J Appl Physiol (1985). 1998; 83(6):1877-83. DOI: 10.1152/jappl.1997.83.6.1877. View

3.
Robergs R, Pearson D, Costill D, Fink W, Pascoe D, Benedict M . Muscle glycogenolysis during differing intensities of weight-resistance exercise. J Appl Physiol (1985). 1991; 70(4):1700-6. DOI: 10.1152/jappl.1991.70.4.1700. View

4.
Jentjens R, van Loon L, Mann C, Wagenmakers A, Jeukendrup A . Addition of protein and amino acids to carbohydrates does not enhance postexercise muscle glycogen synthesis. J Appl Physiol (1985). 2001; 91(2):839-46. DOI: 10.1152/jappl.2001.91.2.839. View

5.
Camera D, West D, Burd N, Phillips S, Garnham A, Hawley J . Low muscle glycogen concentration does not suppress the anabolic response to resistance exercise. J Appl Physiol (1985). 2012; 113(2):206-14. DOI: 10.1152/japplphysiol.00395.2012. View