Hyperkalemia-induced Brugada Pattern with Electrical Alternans

Overview

Journal Ann Noninvasive Electrocardiol

Specialty Cardiology & Vascular Diseases

Date 2013 Jan 26

PMID 23347033

Citations 3

Authors

Renguang Liu

Qinghua Chang

Affiliations

Soon will be listed here.

Abstract

The Brugada syndrome is a genetic disease (mutation of the SCN5A gene) that predisposes to syncope and life-threatening sudden cardiac death. The case highlights the importance of recognizing hyperkalemia, as potential triggers of the acquired Brugada sign with electrical alternans.

Citing Articles

Hyperkalemia-induced Brugada phenocopy: a systematic review of case reports.

Alnajjar A, Ibrahim A, Ellebedy M Clin Res Cardiol. 2025; .

PMID: 39964614 DOI: 10.1007/s00392-025-02607-6.

Hyperkalemia Induced Brugada Phenocopy: A Rare ECG Manifestation.

Ameen M, Akbar G, Abbas N, Mirrani G Case Rep Cardiol. 2017; 2017:9464728.

PMID: 28326201 PMC: 5343243. DOI: 10.1155/2017/9464728.

Autonomic and cardio-respiratory responses to exercise in Brugada Syndrome patients.

Chanavirut R, Makarawate P, Macdonald I, Leelayuwat N J Arrhythm. 2016; 32(5):426-432.

PMID: 27761168 PMC: 5063266. DOI: 10.1016/j.joa.2015.09.001.

Action potential wavelength restitution predicts alternans and arrhythmia in murine Scn5a(+/-) hearts.

Matthews G, Guzadhur L, Sabir I, Grace A, Huang C J Physiol. 2013; 591(17):4167-88.

PMID: 23836691 PMC: 3779110. DOI: 10.1113/jphysiol.2013.254938.

References

Ortega-Carnicer J, Benezet J, Ruiz-Lorenzo F, Alcazar R . Transient Brugada-type electrocardiographic abnormalities in renal failure reversed by dialysis. Resuscitation. 2002; 55(2):215-9. DOI: 10.1016/s0300-9572(02)00210-1. View

Tanawuttiwat T, Harindhanavudhi T, Bhan A, Dia M . Hyperkalemia-induced Brugada pattern: an unusual manifestation. J Cardiovasc Med (Hagerstown). 2009; 11(4):285-7. DOI: 10.2459/JCM.0b013e32832f40bd. View

Littmann L, Monroe M, Taylor 3rd L, Brearley Jr W . The hyperkalemic Brugada sign. J Electrocardiol. 2006; 40(1):53-9. DOI: 10.1016/j.jelectrocard.2006.10.057. View

Irani F, Kasmani R, Kanjwal Y . Hyperkalemia and cocaine induced dynamic Brugada-type electrocardiogram. Eur J Emerg Med. 2009; 17(2):113-5. DOI: 10.1097/MEJ.0b013e32832e46d1. View

Garnier F, Mathe A, Bruyeres R . Images in cardiology: electrical aspects of Brugada: hyperkalaemia and intoxication with phenothiazines. Heart. 2008; 94(12):1578. DOI: 10.1136/hrt.2008.153346. View