Comparing Cognitive and Somatic Symptoms of Depression in Myocardial Infarction Patients and Depressed Patients in Primary and Mental Health Care

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2013 Jan 24

PMID 23342019

Citations 5

Authors

Nynke A Groenewold

Bennard Doornbos

Marij Zuidersma

Nicole Vogelzangs

Brenda W J H Penninx

Andre Aleman

Peter de Jonge

Affiliations

Soon will be listed here.

Abstract

Depression in myocardial infarction patients is often a first episode with a late age of onset. Two studies that compared depressed myocardial infarction patients to psychiatric patients found similar levels of somatic symptoms, and one study reported lower levels of cognitive/affective symptoms in myocardial infarction patients. We hypothesized that myocardial infarction patients with first depression onset at a late age would experience fewer cognitive/affective symptoms than depressed patients without cardiovascular disease. Combined data from two large multicenter depression studies resulted in a sample of 734 depressed individuals (194 myocardial infarction, 214 primary care, and 326 mental health care patients). A structured clinical interview provided information about depression diagnosis. Summed cognitive/affective and somatic symptom levels were compared between groups using analysis of covariance, with and without adjusting for the effects of recurrence and age of onset. Depressed myocardial infarction and primary care patients reported significantly lower cognitive/affective symptom levels than mental health care patients (F (2,682) = 6.043, p = 0.003). Additional analyses showed that the difference between myocardial infarction and mental health care patients disappeared after adjusting for age of onset but not recurrence of depression. These group differences were also supported by data-driven latent class analyses. There were no significant group differences in somatic symptom levels. Depression after myocardial infarction appears to have a different phenomenology than depression observed in mental health care. Future studies should investigate the etiological factors predictive of symptom dimensions in myocardial infarction and late-onset depression patients.

Citing Articles

Virtual Reality-Based Psychotherapy in Social Anxiety Disorder: fMRI Study Using a Self-Referential Task.

Hur J, Shin H, Jung D, Lee H, Lee S, Kim G JMIR Ment Health. 2021; 8(4):e25731.

PMID: 33851931 PMC: 8082384. DOI: 10.2196/25731.

Secondary Prevention of Depressive Prodrome in Adolescents: Before and After Attending a Jogging Program on Campus.

Yen K, Cherng S Int J Environ Res Public Health. 2020; 17(21).

PMID: 33105575 PMC: 7659965. DOI: 10.3390/ijerph17217705.

Association Between Affective-Cognitive Symptoms of Depression and Exacerbation of Crohn's Disease.

Gaines L, Slaughter J, Horst S, Schwartz D, Beaulieu D, Haman K Am J Gastroenterol. 2016; 111(6):864-70.

PMID: 27045927 PMC: 4965803. DOI: 10.1038/ajg.2016.98.

Platelet activating factors are associated with depressive symptoms in coronary artery disease patients: a hypothesis-generating study.

Mazereeuw G, Herrmann N, Xu H, Blanchard A, Figeys D, Oh P Neuropsychiatr Dis Treat. 2015; 11:2309-14.

PMID: 26379437 PMC: 4567245. DOI: 10.2147/NDT.S87111.

Subtypes of depression in cancer patients: an empirically driven approach.

Zhu L, Ranchor A, van der Lee M, Garssen B, Sanderman R, Schroevers M Support Care Cancer. 2015; 24(3):1387-96.

PMID: 26341521 PMC: 4729814. DOI: 10.1007/s00520-015-2919-y.

References

Nicholson A, Kuper H, Hemingway H . Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146 538 participants in 54 observational studies. Eur Heart J. 2006; 27(23):2763-74. DOI: 10.1093/eurheartj/ehl338. View

Ormel J, Oldehinkel A, Brilman E . The interplay and etiological continuity of neuroticism, difficulties, and life events in the etiology of major and subsyndromal, first and recurrent depressive episodes in later life. Am J Psychiatry. 2001; 158(6):885-91. DOI: 10.1176/appi.ajp.158.6.885. View

Bus B, Marijnissen R, Holewijn S, Franke B, Purandare N, de Graaf J . Depressive symptom clusters are differentially associated with atherosclerotic disease. Psychol Med. 2010; 41(7):1419-28. DOI: 10.1017/S0033291710002151. View

Hankin B, Oppenheimer C, Jenness J, Barrocas A, Shapero B, Goldband J . Developmental origins of cognitive vulnerabilities to depression: review of processes contributing to stability and change across time. J Clin Psychol. 2009; 65(12):1327-38. PMC: 3071684. DOI: 10.1002/jclp.20625. View

Thombs B, Ziegelstein R, Pilote L, Dozois D, Beck A, Dobson K . Somatic symptom overlap in Beck Depression Inventory-II scores following myocardial infarction. Br J Psychiatry. 2010; 197(1):61-6. PMC: 2894982. DOI: 10.1192/bjp.bp.109.076596. View

Ormel J, de Jonge P . Unipolar depression and the progression of coronary artery disease: toward an integrative model. Psychother Psychosom. 2011; 80(5):264-74. DOI: 10.1159/000323165. View

Donker T, Comijs H, Cuijpers P, Terluin B, Nolen W, Zitman F . The validity of the Dutch K10 and extended K10 screening scales for depressive and anxiety disorders. Psychiatry Res. 2010; 176(1):45-50. DOI: 10.1016/j.psychres.2009.01.012. View

Korten N, Comijs H, Lamers F, Penninx B . Early and late onset depression in young and middle aged adults: differential symptomatology, characteristics and risk factors?. J Affect Disord. 2012; 138(3):259-67. DOI: 10.1016/j.jad.2012.01.042. View

de Jonge P, Ormel J, van den Brink R, van Melle J, Spijkerman T, Kuijper A . Symptom dimensions of depression following myocardial infarction and their relationship with somatic health status and cardiovascular prognosis. Am J Psychiatry. 2006; 163(1):138-44. DOI: 10.1176/appi.ajp.163.1.138. View

10.

Kroenke K, Spitzer R, Williams J . The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001; 16(9):606-13. PMC: 1495268. DOI: 10.1046/j.1525-1497.2001.016009606.x. View

11.

Alexopoulos G . The vascular depression hypothesis: 10 years later. Biol Psychiatry. 2006; 60(12):1304-5. DOI: 10.1016/j.biopsych.2006.09.006. View

12.

Martens E, Denollet J, Pedersen S, Scherders M, Griez E, Widdershoven J . Relative lack of depressive cognitions in post-myocardial infarction depression. J Affect Disord. 2006; 94(1-3):231-7. DOI: 10.1016/j.jad.2006.04.023. View

13.

Beck A, Ward C, Mendelson M, Mock J, ERBAUGH J . An inventory for measuring depression. Arch Gen Psychiatry. 1961; 4:561-71. DOI: 10.1001/archpsyc.1961.01710120031004. View

14.

van Melle J, de Jonge P, Kuyper A, Honig A, Schene A, Crijns H . Prediction of depressive disorder following myocardial infarction data from the Myocardial INfarction and Depression-Intervention Trial (MIND-IT). Int J Cardiol. 2005; 109(1):88-94. DOI: 10.1016/j.ijcard.2005.05.053. View

15.

Thombs B, Ziegelstein R, Beck C, Pilote L . A general factor model for the Beck Depression Inventory-II: validation in a sample of patients hospitalized with acute myocardial infarction. J Psychosom Res. 2008; 65(2):115-21. DOI: 10.1016/j.jpsychores.2008.02.027. View

16.

Rush A, Gullion C, Basco M, Jarrett R, Trivedi M . The Inventory of Depressive Symptomatology (IDS): psychometric properties. Psychol Med. 1996; 26(3):477-86. DOI: 10.1017/s0033291700035558. View

17.

Sneed J, Kasen S, Cohen P . Early-life risk factors for late-onset depression. Int J Geriatr Psychiatry. 2006; 22(7):663-7. DOI: 10.1002/gps.1727. View

18.

Penninx B, Beekman A, Smit J, Zitman F, Nolen W, Spinhoven P . The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods. Int J Methods Psychiatr Res. 2008; 17(3):121-40. PMC: 6878352. DOI: 10.1002/mpr.256. View

19.

de Jonge P, Mangano D, Whooley M . Differential association of cognitive and somatic depressive symptoms with heart rate variability in patients with stable coronary heart disease: findings from the Heart and Soul Study. Psychosom Med. 2007; 69(8):735-9. PMC: 2776660. DOI: 10.1097/PSY.0b013e31815743ca. View

20.

Corruble E, Gorwood P, Falissard B . Association between age of onset and symptom profiles of late-life depression. Acta Psychiatr Scand. 2008; 118(5):389-94. DOI: 10.1111/j.1600-0447.2008.01239.x. View