Erythema Induratum of Bazin Associated with Addison's Disease: First Description

Overview

Journal Sao Paulo Med J

Specialty General Medicine

Date 2013 Jan 23

PMID 23338738

Authors

Rodrigo Antonio Brandao Neto

Jozelio Freire de Carvalho

Affiliations

Soon will be listed here.

Abstract

Context: Erythema induratum of Bazin (EIB) is considered to be a tuberculid reaction and consists of recurrent painful nodules. The differential diagnosis includes diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum.

Case Report: We report the case of a woman with EIB who developed Addison's disease during treatment with anti-tuberculosis drugs with good response to glucocorticoid replacement. The diagnosis was obtained through the clinical picture, positive tuberculin test and positive BCG (bacillus Calmette-Guérin) test on the histological sample. Anti-tuberculosis drugs and glucocorticoid replacement led to disappearance of the signs and symptoms.

Conclusions: This is the first description of an association between EIB and Addison's disease. It should be borne in mind that tuberculosis is an important etiological factor for Addison's disease.

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