Membrane Receptor Neighborhoods: Snuggling Up to the Nucleus

Overview

Journal Circ Res

Specialty Cardiology & Vascular Diseases

Date 2013 Jan 19

PMID 23329788

Citations 8

Authors

Donald M Bers

Affiliations

Soon will be listed here.

Citing Articles

Inositol 1,4,5-trisphosphate receptors in cardiomyocyte physiology and disease.

Demydenko K, Ekhteraei-Tousi S, Roderick H Philos Trans R Soc Lond B Biol Sci. 2022; 377(1864):20210319.

PMID: 36189803 PMC: 9527928. DOI: 10.1098/rstb.2021.0319.

[Nucleus translocation of membrane/cytoplasm proteins in tumor cells].

Zhu Z, Tan J, Deng H Zhejiang Da Xue Xue Bao Yi Xue Ban. 2019; 48(3):318-325.

PMID: 31496165 PMC: 8800772. DOI: 10.3785/j.issn.1008-9292.2019.06.13.

L-type Ca channels' involvement in IFN-γ-induced signaling in rat ventricular cardiomyocytes.

Mitrokhin V, Filatova T, Shim A, Bilichenko A, Abramochkin D, Kamkin A J Physiol Biochem. 2019; 75(1):109-115.

PMID: 30756238 DOI: 10.1007/s13105-019-00662-y.

Nuclear calcium in cardiac myocytes.

Ljubojevic S, Bers D J Cardiovasc Pharmacol. 2014; 65(3):211-7.

PMID: 25329749 PMC: 4355307. DOI: 10.1097/FJC.0000000000000174.

Nuclear compartmentalization of α1-adrenergic receptor signaling in adult cardiac myocytes.

Wu S, OConnell T J Cardiovasc Pharmacol. 2014; 65(2):91-100.

PMID: 25264754 PMC: 4320670. DOI: 10.1097/FJC.0000000000000165.

References

Kockskamper J, Seidlmayer L, Walther S, Hellenkamp K, Maier L, Pieske B . Endothelin-1 enhances nuclear Ca2+ transients in atrial myocytes through Ins(1,4,5)P3-dependent Ca2+ release from perinuclear Ca2+ stores. J Cell Sci. 2007; 121(Pt 2):186-95. DOI: 10.1242/jcs.021386. View

Zima A, Bare D, Mignery G, Blatter L . IP3-dependent nuclear Ca2+ signalling in the mammalian heart. J Physiol. 2007; 584(Pt 2):601-11. PMC: 2277156. DOI: 10.1113/jphysiol.2007.140731. View

Ibarra C, Vicencio J, Estrada M, Lin Y, Rocco P, Rebellato P . Local control of nuclear calcium signaling in cardiac myocytes by perinuclear microdomains of sarcolemmal insulin-like growth factor 1 receptors. Circ Res. 2012; 112(2):236-45. DOI: 10.1161/CIRCRESAHA.112.273839. View

Ibarra C, Estrada M, Carrasco L, Chiong M, Liberona J, Cardenas C . Insulin-like growth factor-1 induces an inositol 1,4,5-trisphosphate-dependent increase in nuclear and cytosolic calcium in cultured rat cardiac myocytes. J Biol Chem. 2003; 279(9):7554-65. DOI: 10.1074/jbc.M311604200. View

Tadevosyan A, Vaniotis G, Allen B, Hebert T, Nattel S . G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function. J Physiol. 2011; 590(6):1313-30. PMC: 3382322. DOI: 10.1113/jphysiol.2011.222794. View

Ljubojevic S, Walther S, Asgarzoei M, Sedej S, Pieske B, Kockskamper J . In situ calibration of nucleoplasmic versus cytoplasmic Ca²+ concentration in adult cardiomyocytes. Biophys J. 2011; 100(10):2356-66. PMC: 3093572. DOI: 10.1016/j.bpj.2011.03.060. View

Remus T, Zima A, Bossuyt J, Bare D, Martin J, Blatter L . Biosensors to measure inositol 1,4,5-trisphosphate concentration in living cells with spatiotemporal resolution. J Biol Chem. 2005; 281(1):608-16. DOI: 10.1074/jbc.M509645200. View

Wu X, Zhang T, Bossuyt J, Li X, McKinsey T, Dedman J . Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest. 2006; 116(3):675-82. PMC: 1386110. DOI: 10.1172/JCI27374. View

Tadevosyan A, Maguy A, Villeneuve L, Babin J, Bonnefoy A, Allen B . Nuclear-delimited angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression. J Biol Chem. 2010; 285(29):22338-49. PMC: 2903375. DOI: 10.1074/jbc.M110.121749. View

10.

Vaniotis G, Allen B, Hebert T . Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signaling. Am J Physiol Heart Circ Physiol. 2011; 301(5):H1754-64. PMC: 5053813. DOI: 10.1152/ajpheart.00657.2011. View

11.

Wright C, Chen Q, Baye N, Huang Y, Healy C, Kasinathan S . Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes. Circ Res. 2008; 103(9):992-1000. PMC: 2792747. DOI: 10.1161/CIRCRESAHA.108.176024. View

12.

Lipp P, Thomas D, Berridge M, Bootman M . Nuclear calcium signalling by individual cytoplasmic calcium puffs. EMBO J. 1998; 16(23):7166-73. PMC: 1170317. DOI: 10.1093/emboj/16.23.7166. View

13.

Passier R, Zeng H, Frey N, Naya F, Nicol R, McKinsey T . CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo. J Clin Invest. 2000; 105(10):1395-406. PMC: 315462. DOI: 10.1172/JCI8551. View

14.

Wu X, Bers D . Sarcoplasmic reticulum and nuclear envelope are one highly interconnected Ca2+ store throughout cardiac myocyte. Circ Res. 2006; 99(3):283-91. DOI: 10.1161/01.RES.0000233386.02708.72. View

15.

Bare D, Kettlun C, Liang M, Bers D, Mignery G . Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II. J Biol Chem. 2005; 280(16):15912-20. DOI: 10.1074/jbc.M414212200. View

16.

Sachdev D, Yee D . Disrupting insulin-like growth factor signaling as a potential cancer therapy. Mol Cancer Ther. 2007; 6(1):1-12. DOI: 10.1158/1535-7163.MCT-06-0080. View

17.

Allbritton N, Meyer T, Stryer L . Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate. Science. 1992; 258(5089):1812-5. DOI: 10.1126/science.1465619. View

18.

Wright C, Wu S, Dahl E, Sazama A, OConnell T . Nuclear localization drives α1-adrenergic receptor oligomerization and signaling in cardiac myocytes. Cell Signal. 2011; 24(3):794-802. PMC: 3393107. DOI: 10.1016/j.cellsig.2011.11.014. View

19.

Luttrell L, van Biesen T, Hawes B, Koch W, Touhara K, Lefkowitz R . G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor. J Biol Chem. 1995; 270(28):16495-8. DOI: 10.1074/jbc.270.28.16495. View