Chemotherapy Use in Elderly Patients with Soft Tissue Sarcoma: a Population-based Study

Overview

Journal Cancer Invest

Specialty Oncology

Date 2013 Jan 17

PMID 23320812

Citations 5

Authors

Igor Matushansky

Filemon Dela Cruz

Beverly J Insel

Dawn L Hershman

Alfred I Neugut

Affiliations

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Abstract

Adjuvant chemotherapy for soft tissue sarcoma (STS) remains controversial while improvement in survival has never been conclusively demonstrated for metastatic STS. We identified individuals in SEER-Medicare with resected or metastatic STS, 1991-2007. Of 2,382 patients with resected STS, 106 (4.5%) received chemotherapy. High tumor grade, larger tumor size, and malignant fibrous histiocytoma subtype were associated with chemotherapy receipt. Of 365 patients with metastatic STS, 118 (32.4%) received chemotherapy. Younger age, fewer comorbidities, and being married were associated with chemotherapy receipt. Consistent with clinical trials, we found minimal use of chemotherapy. Clinical factors were associated with chemotherapy receipt in nonmetastatic STS.

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