Lyme Disease: Review

Overview

Journal Arch Med Sci

Specialty General Medicine

Date 2013 Jan 16

PMID 23319969

Citations 37

Authors

Grazyna Biesiada

Jacek Czepiel

Maciej R Lesniak

Aleksander Garlicki

Tomasz Mach

Affiliations

Soon will be listed here.

Abstract

Lyme disease is a multi-organ animal-borne disease, caused by spirochetes of Borrelia burgdorferi (Bb), which typically affect the skin, nervous system, musculoskeletal system and heart. A history of confirmed exposure to tick bites, typical signs and symptoms of Lyme borreliosis and positive tests for anti-Bb antibodies, are the basis of a diagnosis. A two-step diagnosis is necessary: the first step is based on a high sensitivity ELISA test with positive results confirmed by a more specific Western blot assay. Antibiotic therapy is curative in most cases, but some patients develop chronic symptoms, which do not respond to antibiotics. The aim of this review is to summarize our current knowledge of the symptoms, clinical diagnosis and treatment of Lyme borreliosis.

Citing Articles

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Case presentation and management of Lyme disease patients: a 9-year retrospective analysis in France.

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Cost of illness in patients with post-treatment Lyme disease syndrome in Belgium.

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Musculoskeletal manifestations of Lyme borreliosis - a review.

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